The C18:3n6/C22:4n6 ratio is a good lipid marker of chronic kidney disease (CKD) progression

Szczuko, Małgorzata; Kaczkan, Małgorzata; Małgorzewicz, Sylwia; Rutkowski, Przemysław; Dębska-Ślizień, Alicja; Stachowska, Ewa

doi:10.1186/s12944-020-01258-y

Lipids in Health and Disease

Table 7 Correlation matrix of the biochemical parameters of men with CKD vs. FFA (selected); p < 0.05

From: The C18:3n6/C22:4n6 ratio is a good lipid marker of chronic kidney disease (CKD) progression

Parameter	C10:0 Capric acid	C16:0 Palmitic acid	C16:1 Palmitoleic acid	C18:0 Stearic acid	C18:1n9 ct Oleic acid	C18:1 tans vaccinic acid	C18:3n3 linolenic acid	C20:1 cis11- eico -sanic acid	C22:4n6 (docosatetraenoate)
Age	0.060	0.276	−0,185	−0,122	− 0.304	0.028	− 0.187	−0.170	0.173
Ca [mg/dl]	−0.103	0.505	−0,111	0,389	−0.412	−0.423	− 0.222	−0.057	− 0.311
I PHOS [mg/dl]	−0.304	− 0.635	−0,201	− 0,352	0.194	0.218	0.438	0.256	0.131
iPTH [pg/ml]	−0.159	−0.595	0,017	−0,092	0.424	0.483	0.473	0.251	0.485
CREA [mg/dl]	0.190	0.109	−0,106	0,195	0.013	0.063	−0.069	−0.298	0.725
HGB [g/dl]	0.261	0.020	−0,075	−0,214	0.197	−0.019	− 0.102	−0.124	0.232
%TSAT [%]	0.075	0.302	−0,074	0,185	−0.333	0.035	0.011	−0.059	0.364
Transferrin	−0.013	0.201	−0,044	0,159	−0.273	−0.458	− 0.375	−0.151	− 0.131
FER [ug/l]	0.433	−0.034	0,021	−0,241	0.186	0.252	−0.144	−0.002	0.218
ALB [g/l]	−0.447	0.064	0,035	0,245	−0.141	−0.165	0.166	−0.191	0.107
Na [mEq/L]	0.057	−0.132	−0,049	0,047	−0.190	0.201	0.131	−0.128	0.364
K [mEq/L]	−0.154	−0.002	− 0,140	0,103	0.254	−0.048	− 0.027	0.115	0.235
Height [cm]	−0.356	−0.038	0,007	−0,165	0.137	0.222	0.121	0.125	−0.067
Weight after [kg]	−0.041	−0.090	− 0,110	−0,134	0.102	0.032	−0.055	0.194	−0.117
Treatment duration [months]	−0.044	−0.150	0,141	−0,117	0.174	0.353	−0.015	0.099	0.436
BMI	0.186	−0.071	−0,141	− 0,015	0.012	− 0.102	−0.109	0.110	−0.030
Body surface [m2]	−0.260	−0.256	− 0,192	−0,254	0.273	0.139	0.274	0.329	−0.215
Kt/V	−0.223	−0.050	0,385	−0,061	0.001	0.283	−0.033	−0.154	0.238
CRP	0.287	−0.177	−0,071	− 0,308	0.191	0.105	−0.221	− 0.044	−0.041
nPCR [g/kg/day]	−0.314	−0.198	− 0,152	0,070	− 0.102	0.032	0.123	0.328	0.005
Ca x P [mg2/dl2]	−0.026	−0.322	− 0,330	0,094	− 0.112	−0.181	0.088	0.098	−0.154

* Average treatment duration 46,29 months; bold text - statistically significant correlation

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ISSN: 1476-511X

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