Table 2 Cox regression analysis for S1P and all-cause death
Model | HR ratio(95%CI) for S1PQ1 | P-value | HR ratio(95%CI) for S1PQ4 | P-value |
|---|---|---|---|---|
S1P Crude HR | 3.271 (1.277–8.381) | 0.014 | 3.870 (1.504–9.960) | 0.005 |
Model 1 S1P + age + gender | 3.267 (1.274–8.378) | 0.014 | 3.885 (1.508–10.008) | 0.005 |
Adjustments for predictors of all-cause death in CHF | ||||
S1P + lgNT-proBNP | 2.634 (1.019–6.808) | 0.046 | 3.504 (1.362–9.017) | 0.009 |
S1P + DBP | 3.197 (1.248–8.188) | 0.015 | 3.984 (1.546–10.265) | 0.004 |
S1P + LVEF% | 2.785 (1.072–7.235) | 0.036 | 3.742 (1.453–9.637) | 0.006 |
S1P + LVEDD | 2.922 (1.131–7.546) | 0.027 | 3.723 (1.447–9.578) | 0.006 |
S1P + LVESD | 2.850 (1.101–7.378) | 0.031 | 3.701 (1.438–9.526) | 0.007 |
S1P + LVEDV | 2.689 (1.032–7.007) | 0.043 | 3.504 (1.360–9.030) | 0.009 |
S1P + LVESV | 2.759 (1.063–7.164) | 0.037 | 3.415 (1.321–8.825) | 0.011 |
Adjustments for independent predictors of all-cause death in CHF | ||||
S1P + lgNT-proBNP+LVEDV | 2.043 (0.771–5.413) | 0.115 | 3.144 (1.220–8.101) | 0.018 |
S1P + lgNT-proBNP+DBP | 2.420 (0.932–6.281) | 0.069 | 3.342 (1.291–8.655) | 0.013 |
S1P + LVEDV+DBP | 2.574 (0.981–6.750) | 0.055 | 3.736 (1.449–9.630) | 0.006 |
Model 2 S1P + MAGGIC score | 2.838 (1.097–7.344) | 0.032 | 3.878 (1.505–9.991) | 0.005 |
Model 3 S1P + MAGGIC score + lgNT-proBNP | 2.525 (0.972–6.563) | 0.057 | 3.418 (1.320–8.849) | 0.011 |