Table 5 Grading of Recommendations Assessment, Development and Evaluation (GRADE) according to Schünemann 2009 [20]
Quality assessment | Summary of findings | Importance | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
No of patients | Effect | Quality | |||||||||
No of studies | Design (Randomized controlled trial) | Limitations | Inconsistency | Indirectness | Imprecision | Other considerations | Omega 3 | Control | SMD [95% Conf. Interval] | ||
PD after 3 months | |||||||||||
5 | Yes | no serious limitations | no serious inconsistencya | no indirectness | serious imprecision | none | 132 | 133 | −3.931 [−4.446,-3.417] | moderate | high |
CAL after 3 months | |||||||||||
5 | Yes | no serious limitations | no serious inconsistencya | no indirectness | serious imprecision | none | 132 | 133 | −3.521 [−3.982,-3.059] | moderate | high |
BOP after 3 months | |||||||||||
1 | Yes | no serious limitations | no serious inconsistency | no indirectness | very serious imprecision | none | 40 | 40 | n/a | low | low |