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Fig. 2 | Lipids in Health and Disease

Fig. 2

From: Hepatic steatosis induced in C57BL/6 mice by a non-ß oxidizable fatty acid analogue is associated with reduced plasma kynurenine metabolites and a modified hepatic NAD+/NADH ratio

Fig. 2

Fatty liver analysis, gene and metabolic indexes related to its oxidative status. a Representative histological images showing liver lipid droplet accumulation under experimental conditions. Control and TTP treated C57BL/6 male liver sections were frozen and stained with oil-red. b Total liver triacylglycerol accretion along dietary intervention. c In vitro palmitoyl-CoA oxidation analysis. d Fatty acyl-CoA oxidase activity was performed in liver post-nuclear fractions. e Total liver arachidonic acid accumulation in C57BL/6 males. f Plasma antioxidant capacity. g Plasma and h liver atherogenicity indexes were calculated from lipid profile. i Gene expression analysis in liver. Data presented are mean ± standard deviation (from six animals per group). Statistical significance between control and TTP was shown as: *P < 0.05; **P < 0.01; ***P < 0.001

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