Table 1 Tryptophan and kynurenine pathway metabolites in plasma after 14 days of 0.9% TTP diet in C57BL/6 male mice (n = 6)

Trp (μM)

114.9 ± 5.92

144.4 ± 1.81

0.0147

Kyn (μM)

1.2 ± 0.02

1.3 ± 0.01

0.0346

Neopt (nM)

1.7 ± 0.10

2.1 ± 0.21

0.2182

AA (nM)

138.5 ± 7.84

83.5 ± 4.96

0.0069

HAA (nM)

21.8 ± 5.06

7.7 ± 0.24

0.0490

KA (nM)

150.9 ± 29.0

48.3 ± 5.19

0.0406

XA (nM)

147.3 ± 21.0

34.3 ± 0.48

0.0095

HK (nM)

86.3 ± 29.6

44.3 ± 14.0

0.1410

QA (nM)

291.0 ± 24.3

223.5 ± 48.8

0.3410

Nam (μM)

2.60 ± 0.37

4.49 ± 0.19

0.0160