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Fig. 4 | Lipids in Health and Disease

Fig. 4

From: A comprehensive metabolic profiling of the metabolically healthy obesity phenotype

Fig. 4

Biological markers differentially regulated in MUO, MHO and NW subjects associate with a number of clinical variables, especially body composition- and lipid-related. The heatmap displays Spearman’s rho (ρ) correlation coefficient for clinical variables (x axis) vs significant variables (y axis), as seen in Figs. 1, 2 and 3. Correlations were calculated using all three groups combined. Abbreviations: 16:1/16:0 ratio, Ratio of palmitoleic acid to palmitic acid; 18:1/18:0 ratio, Ratio of oleic acid to stearic acid; ALAT, Alanine aminotransferase; ALP, Alkaline phosphatase; ApoA-I, Apolipoprotein A-I; ApoB-ApoA-I ratio, Ratio of apolipoprotein B to apolipoprotein A-I; ApoB, Apolipoprotein B; ASAT, Aspartate aminotransferase; BMI, Body mass index; C16:0, Palmitic acid; C16:1, Palmitoleic acid; C18:1,c11, NA; C18:1,c9, Oleic acid; C18:2,n-6, Linoleic acid (LA); C20:0, Arachidic acid; C22:0, Behenic acid; C22:5,n-3, Docosapentaenoic acid (DPA); C23:0, Tricosylic acid; CRP, C-reactive protein; gGT, gamma-Glutamyltransferase; Gp-acetyls, Glycoprotein acetyls, mainly a1-acid glycoprotein; HbA1c, Glycated hemoglobin A1c; HDL-C, HDL cholesterol; HDL-C, Total cholesterol in HDL; HDL-TG, Triglycerides in HDL; HDL, high-density lipoprotein; HDL2-C, Total cholesterol in HDL2; Hip-c, Hip circumference; IDL, Intermediate-density lipoprotein; Isoleucine, Isoleucine; L, Large; LDL-C, LDL cholesterol; LDL-TG, Triglycerides in LDL; LDL, low-density lipoprotein; Leucine, Leucine; M, Medium; MHO, Metabolically healthy obese subjects; MUFA, Monounsaturated fatty acids; MUO, Metabolically unhealthy obese subjects; Phenylalanine, Phenylalanine; Propionate, Propionate; PUFA, Polyunsaturated fatty acids; NW, normal weight subjects; Remnant-C, Remnant cholesterol (non-HDL, non-LDL -cholesterol); S, Small; TC, Total cholesterol; TG-PG ratio, Ratio of triglycerides to phosphoglycerides; TG, Serum total triglycerides; TG, Triglycerides; Valine, Valine; VLDL-C, Total cholesterol in VLDL; VLDL-TG, Triglycerides in VLDL; VLDL, Very low-density lipoprotein; Waist-c, Waist circumference; WH ratio, Waist-hip ratio; XL, Extra-large; XS, Extra-small; XXL, Extremely large

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