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Fig. 2 | Lipids in Health and Disease

Fig. 2

From: The imbalance in the aortic ceramide/sphingosine-1-phosphate rheostat in ovariectomized rats and the preventive effect of estrogen

Fig. 2

Relative mRNA levels of key enzymes involved in ceramide metabolism. Y-axis represents the expression in each group relative to the mean value in the Sham group. a, b and c represent the anabolic pathways, while catabolic pathways are illustrated in d, e, and f. Cerk, ceramide kinase; Asah, acid ceramidase; Sgms, sphingomyelin synthase; LASS, ceramide synthase; SPTLC, serine palmitoyltransferase long chain base subunit; nSMase, neutral sphingomyelinase; aSMase, acid sphingomyelinase; n = 4 for SPTLC1, LASS4, aSMase, Sgms2,and n = 3 for the rest of the genes. * P < 0.05, ** P < 0.01, *** P < 0.001

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Lipids in Health and Disease

ISSN: 1476-511X