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Table 1 Stearoyl-CoA desaturase-1 (SCD1), Delta-5-desaturase (D5D) and Delta-6-desaturase (D6D) with purpose, precursor, product and estimated desaturase activity

From: Fatty acid profile and estimated desaturase activities in whole blood are associated with metabolic health

Desaturase enzyme name

Purpose

Precursor

Product

Estimated desaturase activity

SCD1

Desaturation of monounsaturated fatty acids from saturated fatty acids

   

SCD16

 

C16:0 (palmitic acid)

C16:1n7 (palmitoleic acid)

16:1n7/16:0

SCD18

 

C18:0 (stearic acid)

C18:1n9 (oleic acid)

18:1n9/18:0

D6D

Desaturation of polyunsaturated fatty acids (PUFAs)

C18:2n6 (linoleic acid)

C18:3n6 (γ-linolenic acid)

18:3n6/18:2n6

D5D

Desaturation of polyunsaturated fatty acids (PUFAs)

C20:3n6 (dihomo-γ-linolenic acid)

C20:4n6 (arachidonic acid)

20:4n6/20:3n6