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Table 3 Fatty acid profile and estimated desaturase activity in metabolically healthy and unhealthy subjects

From: Fatty acid profile and estimated desaturase activities in whole blood are associated with metabolic health

Fatty acids, %FAME

Metabolically healthy (n = 150)

Metabolically unhealthy (n = 52)

P

C12:0

0.12 (0.1, 0.14)

0.14 (0.12, 0.17)

0.169

C14:0

0.91 (0.85, 0.98)

1.16 (1.06, 1.25)

< 0.001

C15:0

0.25 (0.24, 0.26)

0.25 (0.23, 0.26)

0.658

C16:0

21.51 (21.25, 21.78)

22.35 (21.95, 22.76)

0.001

C17:0

0.35 (0.34, 0.36)

0.33 (0.32, 0.35)

0.049

C18:0

11.79 (11.62, 11.96)

10.98 (10.72, 11.24)

< 0.001

C20:0

0.09 (0.08, 0.09)

0.09 (0.09, 0.1)

0.167

SFA total

35.03 (34.72, 35.34)

35.3 (34.84, 35.77)

0.323

C16:1 n7

1.36 (1.26, 1.46)

1.72 (1.57, 1.86)

< 0.001

C18:1 n9

19.85 (19.45, 20.24)

22.51 (21.9, 23.11)

< 0.001

C18:1 c11

1.54 (1.49, 1.59)

1.51 (1.44, 1.59)

0.512

C20:1 n9

0.26 (0.24, 0.27)

0.24 (0.22, 0.26)

0.221

MUFA total

23 (22.55, 23.45)

25.98 (25.3, 26.66)

< 0.001

SCD16

0.06 (0.06, 0.07)

0.08 (0.07, 0.08)

< 0.001

SCD18

1.7 (1.64, 1.75)

2.08 (2, 2.16)

< 0.001

D5D

0.01 (0.01, 0.01)

0.01 (0.01, 0.01)

0.081

D6D

5.87 (5.65, 6.09)

5.14 (4.8, 5.48)

< 0.001

C18:2 n6

19.81 (19.34, 20.29)

18.94 (18.22, 19.66)

0.042

C18:3 n6

0.2 (0.18, 0.22)

0.22 (0.19, 0.24)

0.257

C18:3 n3

0.49 (0.46, 0.52)

0.61 (0.56, 0.66)

< 0.001

C20:3 n6

1.4 (1.35, 1.45)

1.38 (1.31, 1.46)

0.694

C20:4 n6

8.03 (7.77, 8.29)

7.01 (6.61, 7.4)

< 0.001

C20:5 n3

1.48 (1.33, 1.63)

1.06 (0.83, 1.29)

0.002

C22:5 n3

1.39 (1.34, 1.44)

1.21 (1.13, 1.28)

< 0.001

C22:6 n3

3.4 (3.25, 3.56)

2.98 (2.74, 3.21)

0.003

PUFA total

36.21 (35.63, 36.79)

33.4 (32.52, 34.28)

< 0.001

ω-3 total

6.77 (6.46, 7.08)

5.85 (5.37, 6.33)

0.001

ω-6 total

29.44 (28.91, 29.98)

27.55 (26.74, 28.35)

< 0.001

  1. P values from linear regression models adjusted for age and sex. Values are estimated marginal means 95% confidence interval). P is significant at 0.05 level. SCD1, Stearoyl-CoA desaturase-1; D5D, delta-5-desaturase; D6D, delta-6-desaturase; SFA, saturated fatty acids; MUFA, monounsaturated fatty acids; PUFA, polyunsaturated fatty acids