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Table 3 Summary of Comparative Outcomes for serum lipid Levels

From: A systematic review and meta-analysis of serum cholesterol and triglyceride levels in patients with Parkinson’s disease

Data type

Item

No. of studies

PD/Control

Main effect

Heterogeneity

Publication bias

Hedges g(95%CI)

z score

p value

Q statistic

df

p value

I2 statistic

Egger intercept

p value

Continuous

TC

8

724/889

-0.29 (−0.46, −0.13)

3.48

0.0005

16.51

7

0.02

58%

−1.9330

0.483

adjustion

7

605/769

−0.21 (− 0.33, − 0.10)

3.69

0.0002

9.23

6

0.16

35%

TG

6

542/865

−0.19 (− 0.31, − 0.08)

3.37

0.0008

9.68

5

0.08

48%

2.8479

0.472

adjustion

5

423/745

−0.26 (−0.39, − 0.13)

4.06

<0.0001

4.13

4

0.38

3%

LDL

6

536/501

−0.31 (−0.49,-0.14)

3.48

0.0005

9.57

5

0.09

48%

−0.9563

0.974

adjustion

5

417/381

−0.26 (− 0.43, − 0.07)

2.74

0.006

6.59

4

0.16

39%

HDL

5

496/472

0.08 (−0.04, 0.21)

1.28

0.20

1.94

4

0.75

0%

0.4329

0.851

Dichotomous

TC

12

0.91 (0.79, 1.04)

1.42

0.16

40.72

11

<0.0001

73%

−0.3306

0.965

adjustion

11

0.86 (0.77, 0.97)

2.55

0.01

24.09

10

0.007

58%

TG

4

0.67 (0.60,0.75)

6.82

<0.00001

3.58

3

0.31

16%

−1.3695

0.107

LDL

4

0.76 (0.59,0.97)

2.23

0.03

16.89

3

0.0007

82%

−2.3686

0.205

  1. Abbreviations: TC total cholesterol, TG triglycerides, LDL low density lipoprotein cholesterol, HDL high density lipoprotein cholesterol, C cholesterol, S serum