Table 1 Subjects’ characteristics according to metabolic syndrome expression
From: Association of common gene-smoking interactions with elevated plasma apolipoprotein B concentration
MetS (−) (n = 956) | MetS (+) (n = 842) | P-value | |
|---|---|---|---|
Age, years | 47.2 ± 0.4 | 51.7 ± 0.3 | < 0.001 |
Female, % | 49.0 | 45.1 | NS |
Total cholesterol, mmol/L | 6.3 ± 0.1 | 6.8 ± 0.1 | < 0.001 |
Total triglyceride, mmol/La | 1.3 (1.0–1.9) | 2.6 (1.9–3.9) | < 0.001 |
LDL-Cholesterol, mmol/L | 4.1 ± 0.1 | 4.1 ± 0.1 | NS |
HDL-Cholesterol, mmol/L | 1.32 ± 0.01 | 0.96 ± 0.01 | < 0.001 |
Total apoB, g/L | 1.12 ± 0.01 | 1.26 ± 0.01 | < 0.001 |
CAD, % | 24.6 | 41.1 | < 0.001 |
Number of carried hyperapoB genotypes, % | NS | ||
0 | 46.2 | 45.0 | |
1 | 41.8 | 40.1 | |
≥ 2 | 12.0 | 14.9 | |
PPARα-L162V, % | 25.3 | 24.8 | NS |
Loss-of-function HeLPL, % | 12.3 | 17.9 | 0.001 |
Apo e4 carrier or E2/2, % | 29.3 | 28.7 | NS |
Apo e4 allele carrier | 3.8 | 4.9 | NS |
Apo E2/2 | 25.5 | 23.8 | NS |
Smoking, % | NS | ||
0–10 cigarette/day | 80.8 | 80.9 | |
> 10 cigarette/day | 19.2 | 19.1 |