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Table 1 Summarization of the relationship between NAFLD and all kinds of extrahepatic cancers

From: Association between nonalcoholic fatty liver disease and extrahepatic cancers: a systematic review and meta-analysis

Types of Cancer

Number of studies

OR/HR/IRR

(95%CI)

I2

Pvalue

Gastrointestinal cancers

 Colorectal cancer

10

1.72

1.40–2.11

83.50%

< 0.01

 Colorectal adenomas

9

1.37

1.29–1.46

49.40%

0.045

Cholangiocarcinoma

 Intrahepatic cholangiocarcinoma

6

2.46

1.77–3.44

72.60%

0.003

 Extrahepatic cholangiocarcinoma

4

2.24

1.58–3.17

68.04%

0.023

Breast cancer

4

1.69

1.44–1.99

0.00%

0.727

Gastric cancer

3

1.74

1.03–2.95

73.60%

0.010

Pancreatic cancer

3

2.12

1.58–2.83

0.00%

0.476

Prostate cancer

3

1.36

1.03–1.79

81.90%

0.001

Esophageal cancer

2

1.77

1.19–2.62

0.00%

0.983

  1. Abbreviation: OR odds ratio, HR hazard ratio, IRR incidence rate ratio, CI confidence interval