Table 1 Baseline characteristics of familial hypercholesterolemia (FH) patients in the HELLAS-FH registry
Adults | Children | ||
|---|---|---|---|
Number of patients | 1423 | 197 | |
Gender (male/female) | 733/690 | 100/97 | |
Age at registration (years) | 51.3 ± 14.3 | 11.0 ± 3.5 | |
Age at diagnosis (years) | 44.3 ± 15.8 | 7.2 ± 3.9 | |
DLCN score | 5 (4–8) | – | |
Systolic blood pressure (mmHg) | 128 ± 14 | 111 ± 13 | |
Diastolic blood pressure (mmHg) | 77 ± 9 | 65 ± 9 | |
Heart rate (bpm) | 74 ± 10 | 79 ± 13 | |
Prevalence of distinctive clinical findings (%) | Corneal arcus below the age of 45 years | 8.3% | 1.0% |
Tendon xanthomas | 5.7% | 2.6% | |
Xanthelasma | 5.9% | 1.0% | |
Body mass index (kg/m2) | 27.0 (24.2–29.7) | 20.0 (17.4–22.4) | |
Hypertension (%) | 28.1 | 0.0 | |
Type 2 diabetes (%) | 7.8 | 0.0 | |
Waist circumference | Male (cm) | 95 (88–103) | 70 (61–80) |
Female (cm) | 88 (80–98) | 65 (57–80) | |
Men > 102 cm (%) | 26.6 | – | |
Women > 88 cm (%) | 49.7 | – | |
Smokers (%) | Active | 24.7 | – |
Former | 9.7 | – | |
Passive | 1.9 | – | |
Never | 63.6 | – | |