Table 1 Meta-analysis of the ADRB3 Trp64Arg polymorphism with adipokines levels
Groups or subgroups | Comparisons (Subjects) | SMD (95% CI) | PHeterogeneity | PSMD |
|---|---|---|---|---|
Leptin | ||||
All | 33 (4999) | 0.14 (0.02–0.26) | < 0.001 | 0.02 |
Studies in HWE | 31 (4594) | 0.12 (0.00–0.24) | < 0.001 | 0.05 |
Caucasian | 19 (3036) | 0.11 (− 0.06–0.28) | < 0.01 | 0.21 |
Asian | 11 (1124) | 0.18 (0.03–0.33) | 0.18 | 0.02 |
Female | 9 (1416) | 0.11 (−0.18–0.41) | < 0.001 | 0.46 |
Male | 9 (1161) | 0.22 (0.02–0.42) | 0.04 | 0.03 |
Obesity | 19 (2418) | 0.08 (−0.09–0.24) | 0.01 | 0.36 |
Healthy subjects | 12 (2384) | 0.19 (0.00–0.38) | < 0.001 | 0.05 |
Adiponectin | ||||
All | 12 (2073) | −0.28 (−0.53--0.02) | < 0.001 | 0.03 |
Studies in HWE | 11 (1800) | − 0.26 (− 0.39--0.13) | < 0.001 | < 0.001 |
Caucasian | 10 (1545) | − 0.08 (− 0.23–0.07) | 0.64 | 0.28 |
Asian | 2 (528) | −0.86 (−1.05--0.66) | 0.95 | < 0.001 |
Obesity | 10 (1545) | − 0.08 (− 0.23–0.07) | 0.64 | 0.28 |