Table 1 Baseline characteristics
All | No event | Event | P value | |
|---|---|---|---|---|
General | ||||
N = | 195 | 103 | 92 | – |
Age in years | 66.9 (10.2) | 66.3 (11.0) | 67.7 (9.2) | 0.358 |
Male | 87.2 (170) | 88.3 (91) | 85.9 (79) | 0.380 |
Received OGTT | 56.4 (110) | 60.2 (62) | 52.2 (48) | 0.163 |
Medical History | ||||
Previous myocardial infarction | 43.1 (84) | 37.9 (39) | 48.9 (45) | 0.079 |
Cardiac bypass surgery | 13.8 (27) | 9.7 (10) | 18.5 (17) | 0.059 |
Previous stroke or TIA | 9.2 (18) | 9.7 (10) | 8.7 (8) | 0.503 |
Peripheral artery disease | 7.7 (15) | 10.7 (11) | 4.3 (4) | 0.081 |
Medication | ||||
Platelet inhibitors | 96.9 (189) | 96.1 (99) | 97.8 (90) | 0.396 |
ACE inhibitors/ARBs | 96.4 (188) | 95.1 (98) | 97.8 (90) | 0.271 |
Beta blockers | 91.8 (179) | 88.3 (91) | 95.7 (88) | 0.054 |
Statins | 97.4 (190) | 98.1 (101) | 96.7 (89) | 0.447 |
Clinical characteristics | ||||
Smoking (active) | 17.4 (34) | 23.3 (24) | 10.9 (10) | 0.017 |
Alcohol regularly | 21.0 (41) | 22.3 (23) | 19.6 (18) | 0.384 |
Positive family history | 34.3 (67) | 35.9 (37) | 32.6 (30) | 0.369 |
Hypertension | 95.9 (187) | 92.2 (95) | 100.0 (92) | 0.005 |
Systolic blood pressure in mmHg | 126.1 (15.1) | 124.4 (13.8) | 128.0 (16.4) | 0.095 |
Diastolic blood pressure in mmHg | 74.6 (8.1) | 74.0 (8.1) | 75.3 (8.1) | 0.246 |
Resting heart rate in min−1 | 66.6 (8.4) | 66.8 (8.2) | 66.4 (8.8) | 0.771 |
LV ejection fraction in % | 62.3 (12.3) | 62.7 (11.9) | 61.9 (12.8) | 0.664 |
Body mass index in kg/m2 | 28.8 (3.9) | 28.4 (4.1) | 29.2 (3.6) | 0.194 |
Waist circumference in cm | 103.8 (10.5) | 103.0 (10.5) | 104.8 (10.4) | 0.224 |
Waist-to-hip ratio | 1.00 (0.06) | 1.00 (0.06) | 1.01 (0.07) | 0.477 |
Metabolic characterization | ||||
Normal glucose tolerance | 29.2 (57) | 33.0 (34) | 25.0 (23) | 0.142 |
Impaired glucose tolerance | 24.1 (47) | 24.3 (25) | 23.9 (22) | |
Diabetes mellitus | 46.7 (91) | 42.7 (44) | 51.1 (47) | |
Metabolic syndrome | 59.5 (116) | 51.5 (53) | 68.5 (63) | 0.011 |
Fasting glucose in mg/dL | 129.9 (38.2) | 128.4 (37.4) | 131.7 (39.2) | 0.557 |
Fasting insulin in μIU/mL | 10.7 (9.7) | 9.9 (7.8) | 11.5 (11.4) | 0.238 |
HOMA index | 3.42 (4.08) | 3.04 (3.29) | 3.83 (4,81) | 0.177 |
HbA1c in % | 6.0 (1.1) | 5.9 (0.8) | 6.2 (1.3) | 0.063 |
Total cholesterol in mg/dL | 174.9 (38.4) | 173.3 (36.3) | 176.6 (40.8) | 0.550 |
HDL cholesterol in mg/dL | 44.9 (13.5) | 44.9 (11.3) | 45.0 (15.7) | 0.970 |
LDL cholesterol in mg/dL | 106.4 (34.1) | 107.0 (33.3) | 105.7 (35.2) | 0.802 |
Non-HDL cholesterol mg/dL | 129.9 (138.2) | 128.4 (37.4) | 131.7 (39.2) | 0.557 |
Fasting triglycerides in mg/dL | 151.1 (95.7) | 135.6 (67.5) | 168.4 (117.7) | 0.016 |
Postprandial 5 h-Tg-AUC in mg/dL | 1065 (599) | 979 (477) | 1161 (701) | 0.033 |
C-reactive protein in mg/dL | 4.8 (8.7) | 4.6 (7.3) | 5.0 (10.1) | 0.741 |