Table 6 A summary of hub genes

RAN

RAN, member RAS oncogene family

GO:0035281 pre-miRNA export from nucleus

hsa03008: Ribosome biogenesis in eukaryotes

hsa03013: RNA transport

CCT7

chaperonin containing TCP1 subunit 7

GO:1904871 positive regulation of protein localization to Cajal body

GO:1904869 regulation of protein localization to Cajal body

GO:1904874 positive regulation of telomerase RNA localization to Cajal body

CSE1L

chromosome segregation 1 like

GO:0006606 protein import into nucleus

GO:0006611 protein export from nucleus

GO:0051170 import into nucleus

SNRPD3

small nuclear ribonucleoprotein D3 polypeptide

GO:0000387 spliceosomal snRNP assembly

GO:0008334 histone mRNA metabolic process

hsa03040: Spliceosome

TUBA1A

tubulin alpha 1a

GO:0097711 ciliary basal body-plasma membrane docking

hsa04540: Gap junction;

hsa04210: Apoptosis

USP14

ubiquitin specific peptidase 14

GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process

GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process

GO:1904293 negative regulation of ERAD pathway

PSMD9

proteasome 26S subunit, non-ATPase 9

GO:0002223 stimulatory C-type lectin receptor signaling pathway

GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent

GO:0046676 negative regulation of insulin secretion

CDK4

cyclin dependent kinase 4

GO:1904637 cellular response to ionomycin; 12-myristate

GO:1904628 cellular response to phorbol 13-acetate

GO:1904636 response to ionomycin

RPL23A

ribosomal protein L23a

GO:0006614 SRP-dependent cotranslational protein targeting to membrane

GO:0006613 cotranslational protein targeting to membrane

hsa03010: Ribosome

XRCC6

X-ray repair cross complementing 6

GO:0075713 establishment of integrated proviral latency

GO:0097680 double-strand break repair via classical nonhomologous end joining

hsa03450: Non-homologous end-joining

EIF2S1

eukaryotic translation initiation factor 2 subunit alpha

GO:1990737 response to manganese-induced endoplasmic reticulum stress

GO:0032057 negative regulation of translational initiation in response to stress;process

hsa04140: Autophagy - animal