Fig. 4
From: High fat diet altered cardiac metabolic gene profile in Psammomys obesus gerbils
Myocardial expression of genes implicated in uptake and metabolism of glucose and fatty acids, including the solute carrier family 2 members 1 (Slc2a1 also called GLUT1; a) and 4 (Slc2a4 also called GLUT4; a); the carnitine palmitoyltransferase1B (CPT1B; b), the CD36 (b) and the fatty acid binding protein 3 (FABP3; b); of transcription factors implicated in cardiac metabolism regulation, including the peroxisome proliferator activated receptors-alpha (PPAR-α; c) and -gamma (PPAR-γ; c); the protein kinase AMP-activated (AMPK; d), pyruvate dehydrogenase kinase 4 (PDK4; d) and uncoupling protein 3 (UCP3; d); and of insulin receptors (IRS)1 and 2 (e) in 16-week normal (n = 10; yellow bars) versus high fat (n = 10; blue bars) diet fed Psammomys obesus gerbils. Values are expressed as mean ± SEM. * 0.01 < P < 0.05, high fat diet- versus normal diet-fed Psammomys obesus animals