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Table 2 Subgroup analysis of association between ApoE alleles / genotypes and diabetic nephropathy

From: ε2 allele and ε2-involved genotypes (ε2/ε2, ε2/ε3, and ε2/ε4) may confer the association of APOE genetic polymorphism with risks of nephropathy in type 2 diabetes: a meta-analysis

Variable

China

 

Other

 

OR

(95% CI)

I2 (%)

OR

(95%CI)

I2 (%)

Alleles

 ε2

2.04

(1.58,2.62)

50

1.56

(0.97,2.53)

70

 ε4

1.26

(0.94,1.71)

68

0.68

(0.51–0.91)

46

Genotypes

 ε2/ε2

2.74

(1.67, 4.49)

1

1.29

(0.52, 3.16)

6

 ε2/ε3

2.09

(1.58, 2.76)

35

1.69

(0.95, 2.99)

69

 ε2/ε4

1.64

(1.08, 2.50)

13

1.88

(0.90, 3.91)

33

 ε3/ε4

1.46

(0.99, 2.15)

71

0.61

(0.44, 0.84)

38

 ε4/ε4

0.80

(0.47, 1.36)

0

0.89

(0.42, 1.89)

6

  1. ApoE alleles (ε2 and ε4) and genotypes (ε2/ε2, ε2/ε3, ε2/ε4, ε3/ε4 and ε4/ε4) were compared with ε3 and ε3/ε3