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Table 4 Sensitivity analysis of association between ApoE genotypes and diabetic nephropathy

From: ε2 allele and ε2-involved genotypes (ε2/ε2, ε2/ε3, and ε2/ε4) may confer the association of APOE genetic polymorphism with risks of nephropathy in type 2 diabetes: a meta-analysis

Study

ε2/ε2

ε2/ε3

ε2/ε4

ε3/ε4

ε4/ε4

Horita et al. [37]

2.27 (1.49, 3.53)

1.91 (1.45, 2.52)

1.70 (1.18, 2.46)

0.99 (0.73, 1.34)

0.73 (0.46, 1.16)

Eto et al. [36]

2.27 (1.50, 3.55)

1.96 (1.48, 2.59)

1.68 (1.16, 2.43)

0.99 (0.72, 1.34)

0.79 (0.50, 1.25)

Kimura et al. [39]

2.27 (1.52, 3.56)

2.01 (1.52, 2.66)

1.86 (1.28, 2.71)

1.01 (0.75, 1.36)

0.84 (0.54, 1.31)

Zhang et al. [30]

2.27 (1.41, 3.36)

1.99 (1.50, 2.63)

1.67 (1.15, 2.42)

0.99 (0.73, 1.34)

0.83 (0.53, 1.28)

Xiang et al. [45]

2.27 (1.48, 3.52)

1.96 (1.48, 2.59)

1.72 (1.19, 2.48)

0.99 (0.73, 1.34)

0.82 (0.53, 1.28)

Ha et al. [46]

2.27 (1.46, 3.47)

1.94 (1.47, 2.57)

1.73 (1.19, 2.50)

0.97 (0.72, 1.32)

0.83 (0.54, 1.30)

Akarsu et al. [47]

2.27 (1.48, 3.50)

1.96 (1.49, 2.59)

1.69 (1.18, 2.44)

0.99 (0.74, 1.34)

0.82 (0.53, 1.27)

Dai et al. [24]

2.27 (1.52, 3.56)

2.02 (1.53, 2.67)

1.70 (1.18, 2.46)

0.97 (0.72, 1.31)

0.83 (0.53, 1.29)

Shen et al. [32]

2.27 (1.54, 3.66)

1.91 (1.45, 2.51)

1.73 (1.19, 2.51)

0.95 (0.71, 1.28)

0.84 (0.54, 1.31)

Zhang et al. [33]

2.27 (1.47, 3.49)

1.94 (1.47, 2.56)

1.66 (1.15, 2.40)

1.00 (0.74, 1.35)

0.80 (0.51, 1.24)

Liu et al. [42]

2.27 (1.53, 3.61)

2.02 (1.52, 2.68)

1.72 (1.19, 2.49)

0.97 (0.72, 1.32)

0.82 (0.53, 1.27)

Park et al. [23]

2.27 (1.52, 3.56)

1.91 (1.45, 2.50)

1.69 (1.18, 2.44)

1.00 (0.74, 1.35)

0.83 (0.53, 1.28)

Liu et al. [34]

2.27 (1.52, 3.56)

1.94 (1.47, 2.56)

1.69 (1.17, 2.44)

0.98 (0.73, 1.32)

0.83 (0.53, 1.28)

Xiong et al. [29]

2.27 (1.54, 3.65)

2.02 (1.53, 2.66)

1.71 (1.18, 2.47)

0.98 (0.73, 1.32)

0.80 (0.51, 1.25)

Hua et al. [27]

2.27 (1.56, 3.74)

1.91 (1.45, 2.52)

1.86 (1.27, 2.71)

1.00 (0.74, 1.35)

0.82 (0.52, 1.28)

Guo et al. [31]

2.27 (1.41, 3.36)

1.95 (1.48, 2.56)

1.74 (1.19, 2.54)

0.98 (0.73, 1.32)

0.83 (0.53, 1.28)

Ng et al. [43]

2.27 (1.58, 3.90)

2.02 (1.50, 2.71)

1.78 (1.21, 2.60)

0.97 (0.71, 1.31)

0.85 (0.55, 1.33)

Zhang et al. [25]

2.27 (1.47, 3.48)

1.97 (1.49, 2.60)

1.67 (1.16, 2.42)

0.95 (0.71, 1.28)

0.84 (0.54, 1.30)

Pan et al. [26]

2.27 (1.58, 3.78)

2.03 (1.54, 2.69)

1.71 (1.18, 2.47)

0.93 (0.70, 1.23)

0.80 (0.51, 1.24)

Ilhan et al. [38]

2.27 (1.64, 3.98)

2.01 (1.52, 2.65)

1.69 (1.18, 2.44)

0.97 (0.72, 1.31)

0.83 (0.53, 1.28)

Kwon et al. [40]

2.27 (1.52, 3.56)

2.03 (1.53, 2.67)

1.68 (1.16, 2.43)

1.02 (0.76, 1.36)

0.84 (0.54, 1.30)

Leiva et al. [41]

2.27 (1.52, 3.56)

2.00 (1.52, 2.63)

1.69 (1.18, 2.44)

1.03 (0.77, 1.38)

0.86 (0.55, 1.34)

Rouzi et al. [15]

2.27 (1.47, 3.49)

1.96 (1.49, 2.58)

1.82 (1.24, 2.65)

0.98 (0.73, 1.32)

0.83 (0.53, 1.28)

Erdogan et al. [35]

2.27 (1.52, 3.56)

2.01 (1.53, 2.65)

1.66 (1.14, 2.39)

1.01 (0.75, 1.36)

0.83 (0.53, 1.28)

Xiang et al. [28]

2.27 (1.52, 3.56)

1.95 (1.47, 2.58)

1.74 (1.20, 2.51)

1.00 (0.74, 1.35)

0.83 (0.53, 1.28)

Reis et al. [44]

2.27 (1.52, 3.56)

2.09 (1.66, 2.64)

1.69 (1.18, 2.44)

1.02 (0.75, 1.37)

0.83 (0.53, 1.28)

Sun et al. [16]

2.55 (1.60, 4.05)

2.03 (1.52, 2.71)

1.55 (1.07, 2.25)

0.94 (0.70, 1.27)

0.83 (0.53, 1.28)

Satirapoj et al. [22]

2.27 (1.59, 3.82)

2.00 (1.51, 2.66)

1.69 (1.18, 2.44)

1.02 (0.76, 1.37)

0.83 (0.53, 1.28)

Wang et al. [17]

2.27 (1.39, 3.32)

1.95 (1.48, 2.58)

1.66 (1.14, 2.41)

1.01 (0.75, 1.36)

0.82 (0.52, 1.30)

Luo et al. [18]

2.27 (1.38, 3.29)

1.89 (1.45, 2.46)

1.50 (1.03, 2.18)

0.92 (0.71, 1.18)

0.75 (0.48, 1.18)

Atta et al. [19]

2.27 (1.52, 3.56)

1.92 (1.47, 2.50)

1.47 (1.01, 2.15)

0.98 (0.73, 1.32)

0.83 (0.53, 1.28)

Jiang et al. [20]

2.27 (1.43, 3.48)

1.98 (1.48, 2.65)

1.66 (1.13, 2.44)

0.99 (0.72, 1.36)

1.03 (0.63, 1.66)

Karimoei et al. [21]

2.27 (1.58, 3.78)

1.99 (1.50, 2.63)

1.76 (1.21, 2.55)

1.02 (0.75, 1.37)

0.87 (0.56, 1.36)

  1. ApoE genotypes (ε2/ε2, ε2/ε3, ε2/ε4, ε3/ε4 and ε4/ε4) were compared with ε3/ε3
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Lipids in Health and Disease

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