Table 1 Exclusion criteria

1) more than 20 g/day of ethanol intake

2) cirrhosis

3) other liver diseases (viral hepatitis, autoimmune hepatitis, drug-induced liver injury, etc.)

4) pancreatitis

5) severe anemia

6) acute and chronic kidney disease

7) cancer

8) pregnancy

9) drug addiction

10) use of the following drugs in the 12 months prior to screening: anti-diabetic drugs, anti-hypertensive drugs, anti-dyslipidemia drugs or folic acid and B vitamins