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Table 3 Sex-specific association of serum lipids with cognitive function score in different BMI categories (Multivariable linear regression)

From: Subgroup analysis of the influence of body mass index on the association between serum lipids and cognitive function in Chinese population

Parameter

Status

Cognitive function scorea

  

Men

Women

Mid-life adults

Older adults

  

β

SE

t

P value

β

SE

t

P value

β

SE

t

P value

β

SE

t

P value

TG, mmol/L

Underweight

2.06

0.88

2.35

0.023

−0.86

1.13

−0.76

0.452

0.25

0.81

0.31

0.758

− 0.13

1.02

− 0.13

0.898

Normal weight

0.26

0.33

0.79

0.429

0.18

0.38

0.48

0.629

0.16

0.32

0.50

0.621

0.30

0.38

0.80

0.426

Overweight

−0.12

0.40

−0.29

0.773

− 0.12

0.41

− 0.29

0.775

0.16

0.38

0.43

0.671

−0.43

− 0.43

− 0.99

0.323

Obese

1.44

0.71

2.03

0.045

−1.05

0.79

− 1.34

0.184

0.29

0.67

0.43

0.669

−0.36

0.93

−0.39

0.700

Severely obese

1.92

1.90

1.01

0.339

1.63

1.67

0.97

0.344

−2.71

1.56

−1.74

0.102

4.05

2.47

1.64

0.127

TC, mmol/L

Underweight

3.67

2.91

1.26

0.210

2.18

3.53

0.62

0.540

4.84

2.73

1.78

0.085

−1.64

3.09

−0.53

0.598

Normal weight

1.62

1.09

1.49

0.136

0.42

1.12

0.37

0.712

1.11

1.05

1.06

0.288

0.92

1.16

0.80

0.425

Overweight

−1.66

1.28

−1.29

0.198

−0.39

1.34

−0.29

0.770

−2.55

1.26

−2.03

0.043

0.56

1.33

0.43

0.671

Obese

−0.28

2.26

−0.12

0.903

2.32

2.08

1.11

0.267

2.27

2.16

1.05

0.295

0.01

2.22

0.00

0.996

Severely obese

−4.84

11.37

−0.43

0.680

1.04

5.11

0.20

0.841

−3.23

5.05

−0.64

0.532

−1.71

13.70

−0.13

0.903

HDL, mmol/L

Underweight

1.79

1.93

0.93

0.358

−1.89

2.53

−0.75

0.460

1.43

2.03

0.71

0.486

−0.67

2.28

−0.29

0.772

Normal weight

0.13

0.70

0.19

0.849

0.79

0.88

0.91

0.365

0.34

0.73

0.47

0.642

0.56

0.78

0.72

0.474

Overweight

0.60

0.90

0.66

0.508

1.89

0.92

2.05

0.041

0.66

0.86

0.77

0.442

2.15

0.94

2.30

0.022

Obese

1.37

1.81

0.76

0.451

5.04

1.62

3.10

0.002

2.39

1.55

1.54

0.126

5.33

2.07

2.58

0.011

Severely obese

−0.94

4.37

−0.22

0.835

2.17

4.72

0.46

0.650

6.53

3.53

1.85

0.083

−2.55

5.81

−0.44

0.669

LDL, mmol/L

Underweight

−1.10

1.64

−0.67

0.505

2.90

2.14

1.35

0.184

2.27

1.58

1.44

0.159

−1.29

1.85

−0.70

0.487

Normal weight

0.77

0.61

1.27

0.205

−0.12

0.70

−0.17

0.869

0.18

0.61

0.30

0.763

0.55

0.69

0.79

0.428

Overweight

−0.33

0.67

− 0.50

0.620

− 0.54

0.80

− 0.68

0.498

− 0.96

0.70

−1.36

0.173

−0.11

0.74

−0.15

0.879

Obese

−1.64

1.27

−1.29

0.200

1.13

1.29

0.88

0.383

0.54

1.24

0.43

0.667

−0.46

1.36

−0.34

0.734

Severely obese

−8.23

5.62

−1.47

0.177

−2.53

2.00

−1.27

0.221

−0.97

2.76

−0.35

0.731

−4.20

3.53

−1.19

0.257

  1. Regression model (age subgroups): adjusted for gender, age, nationality, BMI, SBP, DBP, smoking status, alcohol consumption and education level;
  2. Bold value means P < 0.05
  3. β Unstandardized Beta, SE standard Error, TG triglycerides, TC total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol
  4. a Regression model (gender subgroups): adjusted for age, nationality, BMI, SBP, DBP, smoking status, alcohol consumption and education level
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Lipids in Health and Disease

ISSN: 1476-511X