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Table 1 Clinical Data of The Study Population by TC Quartiles at Gestational Diabetes Diagnosis*

From: The relationship between total cholesterol and postpartum impaired glucose tolerance in women with gestational diabetes mellitus

 

Total

TC Quartiles at GDM diagnosis

(IQR)

N = 845

First

(3.4, 5.5)

N = 212

Second

(5.6, 6.2)

N = 202

Third

(6.3, 7.0)

N = 226

Four

(7.1, 9.2)

N = 205

Demographic data

 Maternal age (year)

33.0 (6.0)

34.0 (7.3)

32.0 (6.0)

32.5 (6.0)

33.0 (8.0)

 GA at OGTT (week)

25.14 (1.57)

25.14 (1.85)

25.14 (1.57)

25.29 (1.43)

25.14 (1.57)

 Pre-pregnancy BMI (kg m−2)

21.37 (3.91)

22.27 (4.06) a, b, c

21.48 (3.79)

21.14 (3.79)

20.96 (3.96)

 GWG (kg)

11.00 (5.20)

10.20 (5.50)

11.00 (5.00)

11.00 (5.08)

11.00 (4.50)

 TC (mmol l−1)

6.30 (1.50)

4.00 (1.80)

6.00 (1.30)

6.60 (0.40)

7.60 (0.80)

 TG (mmol l−1)

2.21 (1.05)

2.11 (1.03)c

2.21 (1.10)

2.25 (1.12)

2.36 (1.00)

 LDL-c (mmol l−1)

1.96 (0.50)

1.73 (0.40) a, b, c

1.88 (0.39) d, e

2.05 (0.46) f

2.23 (0.45)

 HDL-c (mmol l−1)

3.51 (1.02)

2.66 (0.57) a, b, c

3.28 (0.36) d, e

3.75 (0.38) f

4.37 (0.66)

Medical and obstetric history

 Primipara (%)

498 (58.9)

119 (23.9)

122 (24.5)

139 (27.9)

118 (23.7)

 Spontaneous abortion (%)

146 (17.3)

45 (30.8)

36 (24.7)

31 (21.2)

34 (23.3)

 Adverse pregnancy outcomes (%)

17 (2.0)

5 (29.5)

6 (35.3)

3 (17.6)

3 (17.6)

Pregnant and postpartum data

 PTB (%)

89 (10.5)

31 (34.8)

21 (23.6)

18 (20.2)

19 (21.3)

 GA at delivery (weeks)

38.71 (1.57)

38.64 (1.71)

38.86 (1.60)

38.86 (1.57)

38.79 (1.43)

 Caesarean delivery (%)

450 (53.2)

130 (28.9) b, c

107 (23.8)

115 (25.6)

98 (21.8)

 Neonatal weight (kg)

3.12 (0.54)

3.11 (0.63)

3.10 (0.56)

3.15 (0.50)

3.10 (0.42)

 postpartum OGTT timing (weeks)

7.57 (1.82)

7.43 (1.85)

7.43 (1.32)

7.71 (2.04)

7.50 (1.71)

Postpartum OGTT (mmol l−1)

 Fasting

4.8 (0.6)

4.8 (0.6)

4.8 (0.5) e

4.8 (0.7)

4.9 (0.6)

 2-h

7.1 (2.2)

6.4 (1.3) b, c

6.4 (1.5) d, e

7.9 (2.7) f

8.6 (1.2)

 IFG (%)

3 (0.4)

1 (33.3)

0

1 (33.3)

1 (33.3)

 IGT (%)

267 (31.6)

83 (31.1) c

64 (24.0)

70 (26.2)

50 (18.7)

 Type 2 diabetes (%)

31 (3.7)

15 (48.4) b, c

6 (19.4)

5 (16.1)

5 (16.1)

 Prediabetes (%)

270 (31.9)

84 (31.1) c

64 (23.7)

71 (26.3)

51 (18.9)

 Postpartum glucose intolerance (%)

301 (35.6)

99 (32.9) a, b, c

70 (23.3)

76 (25.2)

56 (18.6)

  1. TC total cholesterol, GDM gestational diabetes mellitus, BMI body mass index, GA gestational age, GWG gestational weight gain, PTB preterm birth, OGTT oral glucose tolerance test, IFG impaired fasting glucose, IGT impaired glucose tolerance
  2. *data are shown as median (IQR) or number (%)
  3. a, b, c, d, e, f Indicates a significant difference between first and second quartile, first and third quartile, first and fourth quartile, second and third quartile, second and fourth quartile, third and fourth quartile, respectively
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Lipids in Health and Disease

ISSN: 1476-511X