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Table 2 Hazard Ratio of The Association Between TC Quartiles at the time of GDM Diagnosis and Risk of Postpartum Impaired Glucose Tolerance (N = 845)

From: The relationship between total cholesterol and postpartum impaired glucose tolerance in women with gestational diabetes mellitus

 

N (%)

HR (95%CI)

P

Adjusted HR (95%CI)a

P

IGT

First

83 (30.6)

Reference

 

Reference

 

Second

64 (23.6)

0.875 (0.631, 1.214)

0.423

0.892 (0.642, 1.239)

0.494

Third

70 (25.9)

0.704 (0.512, 0.968)

0.031

0.703 (0.510, 0.971)

0.032

Fourth

54 (19.9)

0.562 (0.395, 0.799)

0.001

0.569 (0.400, 0.811)

0.002

Prediabetesb

First

84 (30.7)

Reference

 

Reference

 

Second

64 (23.4)

0.864 (0.623, 1.197)

0.380

0.880 (0.634, 1.222)

0.446

Third

71 (25.9)

0.705 (0.514, 0.968)

0.031

0.705 (0.512, 0.971)

0.032

Fourth

55 (20.0)

0.566 (0.400, 0.803)

0.001

0.574 (0.404, 0.815)

0.002

Type 2 diabetes

First

15 (48.4)

Reference

 

Reference

 

Second

6 (19.4)

0.457 (0.177, 1.181)

0.106

0.455 (0.176, 1.174)

0.103

Third

5 (16.1)

0.242 (0.085, 0.687)

0.008

0.239 (0.084, 0.680)

0.007

Fourth

5 (16.1)

0.296 (0.106, 0.825)

0.020

0.293 (0.105, 0.817)

0.019

Postpartum glucose intolerancec

First

99 (32.9)

Reference

 

Reference

 

Second

70 (23.3)

0.802 (0.590, 1.091)

0.802

0.814 (0.598, 1.109)

0.192

Third

76 (25.2)

0.634 (0.470, 0.856)

0.003

0.632 (0.467, 0.855)

0.003

Fourth

56 (18.6)

0.526 (0.379, 0.731)

0.000

0.531 (0.382, 0.739)

0.000

  1. TC total cholesterol, GDM gestational diabetes mellitus, HR hazard ratio, CI confidential interval, IGT impaired glucose tolerance
  2. aadjusted for maternal age, pre-pregnancy BMI, time of diagnostic OGTT, time of postpartum OGTT, the concentrations of TG, HDL-c, LDL-c at time of GDM diagnosis and insulin treatment or not
  3. bincluding both IFG and IGT
  4. cincluding IFG, IGT and type 2 diabetes