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Table 2 Association* of lipoprotein and insulin resistance score components with lipid species factors in the Lipid Lowering Drugs and Diet Network Study (n = 980)

From: A lipidome-wide association study of the lipoprotein insulin resistance index

 Storage lipids (Factor 1)Non-storage lipids (Factor 2)Mixed lipids (Factor 3)
ScoresβSEP-valueβSEP-valueβSEP-value
LPIR0.0250.0014.52E-71−0.0130.0012.78E-180.0210.0025.84E-41
VLDL_Size−0.0040.0040.356−0.0130.0040.0020.0460.0046.06E-27
Large_VLDL0.0560.0031.52E-65−0.01610.0034.11E-060.0690.0031.67E-96
LDL_Size0.1500.0114.90E-43−0.0680.0111.10E-090.0080.0130.533
Small_LDL0.2150.0162.77E-40−0.0280.0170.0960.0330.0180.096
HDL_Size0.0660.0053.62E-45−0.0360.0056.36E-140.0080.0050.138
Large_HDL0.1130.0072.87E-54−0.0790.0071.05E-270.0180.0090.037
HOMA-IR0.0800.0141.44E-08−0.0700.0131.04E-070.1070.0156.30E-13
  1. *Adjusted for age, sex, BMI, center and family relationship
  2. P-values were FDR corrected to account for multiple comparisons. Bolded values indicate statistical significance (at P-values < 0.05)
  3. Abbreviations: SE Standard error, LPIR Lipoprotein insulin resistance, VLDL Very low-density lipoprotein, LDL Dense low-density lipoprotein, HDL High-density lipoprotein, HOMA-IR Homeostatic model assessment-insulin resistance