Association between the non-HDL-cholesterol-to-HDL-cholesterol ratio and the risk of gallbladder polyp formation among men: a retrospective cohort study

Table 4 Multiple Cox regression analysis of non-HDL-c/HDL-c ratio and risk for presence of GBPs in subgroups

	No. of events	Hazard ratio (95% CI)	P-value	P for interaction
Age (yr)				0.8882
< 65	125	1.24 (0.93, 1.66)	0.1381
> =65	12	1.32 (0.60, 2.88)	0.4889
BMI (kg/m²)				0.3464
< 25	64	1.43 (0.97, 2.10)	0.0672
> =25	61	1.10 (0.74, 1.63)	0.6333
HBsAg				0.7683
0	124	1.27 (0.96, 1.69)	0.0998
1	13	1.11 (0.48, 2.59)	0.802
Hypertension				0.5645
0	107	1.20 (0.88, 1.64)	0.2442
1	30	1.41 (0.87, 2.30)	0.1625
TGW				1
0	137	1.25 (0.96, 1.65)	0.103
1	0	̶ ^a	1
Smoking				0.6484
0	122	1.23 (0.93, 1.64)	0.1428
1	14	1.49 (0.67, 3.31)	0.3232
Drinking				0.8875
0	129	1.25 (0.95, 1.65)	0.1093
1	7	1.37 (0.40, 4.68)	0.6176

P for interaction stands for interaction between the non-HDL-c/HDL-c ratio and each subgroup
GBPs, gallbladder polyps; HDL-c, high-density lipoprotein -cholesterol; BMI, body mass index; HBsAg, hepatitis B surface antigen; TGW, thickening of the gallbladder wall
Data are adjusted for age, body mass index, alanine aminotransferase, aspartate aminotransferase, gamma-glutamyl transpeptidase, alkaline phosphatase, triglyceride, uric acid, fasting plasma glucose, hepatitis B surface antigen, hypertension, and thickening of the gallbladder wall, smoking and drinking
^aThe model failed because of the small sample size

ISSN: 1476-511X