Table 2 The distributions of genotypes and alleles of the APOE gene in the CAD patients and control participants
APOE | CAD patients | Controls | P value |
|---|---|---|---|
(n = 653) | (n = 646) | ||
Genotype | |||
E2/E2 | 3 (0.46) | 2 (0.31) | Â |
E2/E3 | 66 (10.11) | 91 (14.09) | Â |
E3/E3 | 442 (67.69) | 448 (69.35) | Â |
E3/E4 | 125 (19.14) | 92 (14.24) | Â |
E2/E4 | 6 (0.92) | 10 (1.55) | 0.011 |
E4/E4 | 11 (1.68) | 3 (0.46) | |
HWE | χ2 = 1.79, P = 0.77 | χ2 = 2.06, P = 0.73 |  |
Allele | |||
ε2 | 78 (5.97) | 105 (8.13) |  |
ε3 | 1075 (82.31) | 1079 (83.51) | 0.003 |
ε4 | 153 (11.72) | 108 (8.46) | |