Table 1 Baseline characteristics of the study participants according to baseline LDL-C/HDL-C ratio quartiles
Baseline characteristics | LDL-C/HDL-C ratio quartilesa | P value | |||
|---|---|---|---|---|---|
~ 1.68 (n = 3405) | 1.69 ~ 2.20 (n = 3405) | 2.21 ~ 2.78 (n = 3408) | 2.79 ~ (n = 3394) | ||
Total | |||||
 Age (years) |  |  |  |  | < 0.001 |
   < 45 | 2341 | 2020 | 1906 | 1956 |  |
   ≥ 45 | 1064 | 1385 | 1502 | 1438 |  |
 Sex |  |  |  |  | < 0.001 |
  Men | 988 | 1591 | 2120 | 2502 |  |
  Women | 2417 | 1814 | 1288 | 892 |  |
Height (cm) | 164.33 ± 7.54 | 166.06 ± 8.04 | 167.92 ± 8 | 169.3 ± 7.65 | < 0.001 |
Weight (kg) | 61.73 ± 11.18 | 67.7 ± 11.95 | 72.69 ± 12.18 | 76.73 ± 12.23 | < 0.001 |
BMI (kg/m2) | 22.76 ± 3.17 | 24.45 ± 3.27 | 25.67 ± 3.25 | 26.68 ± 3.23 | < 0.001 |
Waist (cm) | 75.88 ± 9.48 | 81.57 ± 9.84 | 85.68 ± 9.53 | 89.07 ± 9.03 | < 0.001 |
Heart rate (beats/min) | 76.65 ± 10.45 | 76.75 ± 10.31 | 76.98 ± 10.14 | 78.45 ± 10.8 | < 0.001 |
SUA (mmol/L) | 278.92 ± 75.57 | 310.79 ± 80.95 | 341.45 ± 84.64 | 364.35 ± 84.22 | < 0.001 |
Creatinine (μmol/L) | 70.49 ± 19.59 | 75.22 ± 22.18 | 78.34 ± 15.76 | 79.61 ± 15.59 | < 0.001 |
TC (mmol/L) | 4.24 ± 0.77 | 4.58 ± 0.75 | 4.85 ± 0.78 | 5.32 ± 0.85 | < 0.001 |
TG (mmol/L) (median [range]) | 0.75(0.23–17.70) | 1.02(0.30–18.41) | 1.37(0.39–17.85) | 1.73(0.43–15.81) | < 0.001 |
ALT (U/L) | 17.62 ± 12.27 | 21.31 ± 18.76 | 24.71 ± 17.11 | 30.06 ± 22.8 | < 0.001 |
AST (U/L) | 19.29 ± 8.09 | 20.56 ± 10.76 | 21.27 ± 8.79 | 22.95 ± 10.41 | < 0.001 |
 Lipid lowering treatment |  |  |  |  | 0.039 |
  No | 3395 | 3394 | 3384 | 3380 |  |
  Yes | 10 | 11 | 24 | 14 |  |
 Smoking |  |  |  |  | < 0.001 |
  Never | 2731 | 2415 | 2184 | 1991 |  |
  Ever | 313 | 485 | 566 | 650 |  |
  Current | 361 | 504 | 658 | 753 |  |
 Drinking |  |  |  |  | < 0.001 |
  Never | 2574 | 2204 | 1808 | 1597 |  |
  Ever | 265 | 336 | 400 | 479 |  |
  Current | 566 | 865 | 1200 | 1318 |  |
 Hypertension |  |  |  |  | < 0.001 |
  No | 3081 | 2854 | 2671 | 2522 |  |
  Yes | 324 | 551 | 737 | 872 |  |
 T2DM |  |  |  |  | < 0.001 |
  No | 3331 | 3273 | 3216 | 3143 |  |
  Yes | 74 | 132 | 192 | 251 |  |
 Fatty liver |  |  |  |  | < 0.001 |
  No | 3025 | 2532 | 1972 | 1400 |  |
  Yes | 379 | 869 | 1435 | 1992 |  |