LDL-cholesterol to HDL-cholesterol ratio discordance with lipid parameters and carotid intima-media thickness: a cohort study in China

Table 2 Association between LDL-C/HDL-C ratio concordance with TC and CIMT risk

	No. of participants/cases	Model 1^a (HR (95%CI))	Model 2^b (HR (95%%CI))	Model 3^c (HR (95%%CI))
Total
Concordantly low LDL-C/HDL-C ratio and low TC	8119/923	1	1	1
Discordantly low LDL-C/HDL-C ratio and high TC	2060/383	1.00 (0.89, 1.13)	1.04 (0.92, 1.17)	1.04 (0.92, 1.18)
Discordantly high LDL-C/HDL-C ratio and low TC	1620/269	1.59 (1.38, 1.83)	1.55 (1.34, 1.78)	1.54 (1.33, 1.77)
Concordantly high LDL-C/HDL-C ratio and high TC	1812/420	1.66 (1.47, 1.86)	1.65 (1.45, 1.87)	1.64 (1.45, 1.86)
Sensitivity analysis by excluding CIMT in the first 2 years
Concordantly low LDL-C/HDL-C ratio and low TC	7915/719	1	1	1
Discordantly low LDL-C/HDL-C ratio and high TC	2013/336	1.06 (0.93, 1.21)	1.09 (0.95, 1.24)	1.1 (0.96, 1.25)
Discordantly high LDL-C/HDL-C ratio and low TC	1561/210	1.65 (1.41, 1.93)	1.60 (1.37, 1.89)	1.60 (1.36, 1.87)
Concordantly high LDL-C/HDL-C ratio and high TC	1720/328	1.63 (1.42, 1.86)	1.61 (1.4, 1.85)	1.61 (1.40, 1.85)

^aModel 1: adjusted for age, gender at baseline
^bModel 2: adjusted for age, gender, BMI, smoking, drinking, WC, TC, TG, creatinine, lipid-lowering medications, T2DM, hypertension, and fatty liver at baseline
^cModel 3: adjusted for age, gender, BMI, smoking, drinking, WC, TC, TG, creatinine, WBC, lipid-lowering medications, T2DM, hypertension, and fatty liver at baseline

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