LDL-cholesterol to HDL-cholesterol ratio discordance with lipid parameters and carotid intima-media thickness: a cohort study in China

Table 3 Association between LDL-C/HDL-C ratio concordance with TG and CIMT risk

	No. of participants/cases	Model 1^a (HR (95%CI))	Model 2^b (HR (95%%CI))	Model 3^c (HR (95%%CI))
Total
Concordantly low LDL-C/HDL-C ratio and low TG	8208/995	1	1	1
Discordantly low LDL-C/HDL-C ratio and high TG	1971/311	0.98 (0.86, 1.11)	0.86 (0.75, 0.99)	0.85 (0.74, 0.97)
Discordantly high LDL-C/HDL-C ratio and low TG	1648/309	1.68 (1.48, 1.92)	1.56 (1.36, 1.79)	1.53 (1.33, 1.76)
Concordantly high LDL-C/HDL-C ratio and TG	1784/380	1.57 (1.39, 1.78)	1.37 (1.19, 1.57)	1.34 (1.17, 1.55)
Sensitivity analysis by excluding CIMT in the first 2 years
Concordantly low LDL-C/HDL-C ratio and low TG	8004/719	1	1	1
Discordantly low LDL-C/HDL-C ratio and high TG	1924/336	1.01 (0.88, 1.16)	0.89 (0.77, 1.03)	0.88 (0.76, 1.02)
Discordantly high LDL-C/HDL-C ratio and low TG	1577/210	1.69 (1.46, 1.96)	1.6 (1.37, 1.86)	1.57 (1.35, 1.83)
Concordantly high LDL-C/HDL-C ratio and TG	1704/328	1.55 (1.35, 1.78)	1.36 (1.17, 1.58)	1.36 (1.17, 1.58)

^aModel 1: adjusted for age, gender at baseline
^bModel 2: adjusted for age, gender, BMI, smoking, drinking, WC, TC, TG, creatinine, lipid-lowering medications, T2DM, hypertension, and fatty liver at baseline
^cModel 3: adjusted for age, gender, BMI, smoking, drinking, WC, TC, TG, creatinine, WBC, lipid-lowering medications, T2DM, hypertension, and fatty liver at baseline

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