| Variable | Model 1 | Model 2 |
|---|
| β | OR (95%CI) | P | β | OR (95%CI) | P |
|---|
| BMI (kg/m2) | −0.023 | 0.98(0.79–1.22) | 0.836 | 0.013 | 1.00(0.80–1.24) | 0.977 |
| Smoking, Y/N | 0.291 | 1.34(1.05–1.71) | 0.019 | 0.384 | 1.38(1.08–1.75) | 0.01 |
| Drinking, Y/N | −0.705 | 0.49 (0.36–0.68) | < 0.001 | − 0.709 | 0.48(0.35–0.66) | < 0.001 |
| HBP, Y/N | 0.563 | 1.76(1.43–2.17) | < 0.001 | 0.556 | 1.73(1.40–2.12) | < 0.001 |
| DM, Y/N | 0.300 | 1.35 (1.05–1.73) | 0.018 | 0.35 | 1.37(1.07–1.76) | 0.013 |
| WBC (109/L), H/L | 0.220 | 1.25(1.01–1.53) | 0.039 | 0.166 | 1.24(1.01–1.52) | 0.044 |
| Bilirubin(mg/L), H/L | −1.046 | 0.35(0.29–0.43) | < 0.001 | − 0.94 | 0.49(0.40–0.61) | < 0.001 |
| TG (mmol/L), H/L | 0.989 | 2.69(2.12–3.40) | < 0.001 | * | * | * |
| TC (mmol/L), H/L | −1.037 | 0.34(0.28–0.44) | < 0.001 | − 0.253 | 0.36(0.29–0.44) | < 0.001 |
| HDL-C (mmol/L), H/L | −0.989 | 0.37(0.30–0.47) | < 0.001 | * | * | * |
| TG/HDL-C, H/L | * | * | * | 1.415 | 4.45(3.52–5.64) | < 0.001 |
- multivariate regression analysis was performed. The dependent variable was CAD. Modle1: the mediators were TG and HDL-C; Modle2: the mediator was TG/HDL-C. Variables showing significance value< 0.05 in univariate analysis were included in the multivariate analysis. BMI body mass index; HBP hypertension; DM diabetes mellitus; TG triglyceride; TC total cholesterol; HDL-C high density lipoprotein cholesterol; WBC white blood cells