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Table 2 Multivariate regression analysis on the relationships between smoking, lipid and CAD risk

From: Mediating effects of lipids on the association between smoking and coronary artery disease risk among Chinese

Variable

Model 1

Model 2

β

OR (95%CI)

P

β

OR (95%CI)

P

BMI (kg/m2)

−0.023

0.98(0.79–1.22)

0.836

0.013

1.00(0.80–1.24)

0.977

Smoking, Y/N

0.291

1.34(1.05–1.71)

0.019

0.384

1.38(1.08–1.75)

0.01

Drinking, Y/N

−0.705

0.49 (0.36–0.68)

< 0.001

− 0.709

0.48(0.35–0.66)

< 0.001

HBP, Y/N

0.563

1.76(1.43–2.17)

< 0.001

0.556

1.73(1.40–2.12)

< 0.001

DM, Y/N

0.300

1.35 (1.05–1.73)

0.018

0.35

1.37(1.07–1.76)

0.013

WBC (109/L), H/L

0.220

1.25(1.01–1.53)

0.039

0.166

1.24(1.01–1.52)

0.044

Bilirubin(mg/L), H/L

−1.046

0.35(0.29–0.43)

< 0.001

− 0.94

0.49(0.40–0.61)

< 0.001

TG (mmol/L), H/L

0.989

2.69(2.12–3.40)

< 0.001

*

*

*

TC (mmol/L), H/L

−1.037

0.34(0.28–0.44)

< 0.001

− 0.253

0.36(0.29–0.44)

< 0.001

HDL-C (mmol/L), H/L

−0.989

0.37(0.30–0.47)

< 0.001

*

*

*

TG/HDL-C, H/L

*

*

*

1.415

4.45(3.52–5.64)

< 0.001

  1. multivariate regression analysis was performed. The dependent variable was CAD. Modle1: the mediators were TG and HDL-C; Modle2: the mediator was TG/HDL-C. Variables showing significance value< 0.05 in univariate analysis were included in the multivariate analysis. BMI body mass index; HBP hypertension; DM diabetes mellitus; TG triglyceride; TC total cholesterol; HDL-C high density lipoprotein cholesterol; WBC white blood cells
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Lipids in Health and Disease

ISSN: 1476-511X