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Table 2 Multivariate regression analysis on the relationships between smoking, lipid and CAD risk

From: Mediating effects of lipids on the association between smoking and coronary artery disease risk among Chinese

VariableModel 1Model 2
βOR (95%CI)PβOR (95%CI)P
BMI (kg/m2)−0.0230.98(0.79–1.22)0.8360.0131.00(0.80–1.24)0.977
Smoking, Y/N0.2911.34(1.05–1.71)0.0190.3841.38(1.08–1.75)0.01
Drinking, Y/N−0.7050.49 (0.36–0.68)< 0.001− 0.7090.48(0.35–0.66)< 0.001
HBP, Y/N0.5631.76(1.43–2.17)< 0.0010.5561.73(1.40–2.12)< 0.001
DM, Y/N0.3001.35 (1.05–1.73)0.0180.351.37(1.07–1.76)0.013
WBC (109/L), H/L0.2201.25(1.01–1.53)0.0390.1661.24(1.01–1.52)0.044
Bilirubin(mg/L), H/L−1.0460.35(0.29–0.43)< 0.001− 0.940.49(0.40–0.61)< 0.001
TG (mmol/L), H/L0.9892.69(2.12–3.40)< 0.001***
TC (mmol/L), H/L−1.0370.34(0.28–0.44)< 0.001− 0.2530.36(0.29–0.44)< 0.001
HDL-C (mmol/L), H/L−0.9890.37(0.30–0.47)< 0.001***
TG/HDL-C, H/L***1.4154.45(3.52–5.64)< 0.001
  1. multivariate regression analysis was performed. The dependent variable was CAD. Modle1: the mediators were TG and HDL-C; Modle2: the mediator was TG/HDL-C. Variables showing significance value< 0.05 in univariate analysis were included in the multivariate analysis. BMI body mass index; HBP hypertension; DM diabetes mellitus; TG triglyceride; TC total cholesterol; HDL-C high density lipoprotein cholesterol; WBC white blood cells