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Table 1 Clinical and Biochemistry characteristics of Patients

From: Association between ceramides and coronary artery stenosis in patients with coronary artery disease

Characteristic

Coronary Stenosis

P

< 25%, N = 60

25–50%, N = 47

50–75%, N = 78

>75%, N =368

Age, yrs

56 ± 10

61 ± 9

59 ± 10

60 ± 11

0.055

Female

35 (58.3%)

11 (23.4%)

15 (19.2%)

94(25.6%)

< 0.001

BMI, kg/m2

25.7 ± 5.1

25.3 ± 2.6

26.8 ± 6.4

25.4 ± 5.2

0.302

Smoking

19 (31.7%)

25 (52.1%)

48(61.5%)

198 (53.8%)

0.02

Diabetes

13 (21.7%)

15 (31.3%)

28 (35.9%)

123 (33.4%)

0.224

hypertension

31 (51.7%)

28(58.3%)

46(60.0%)

255 (69.3%)

0.021

Prior MI/CI

3 (5.0%)

6 (12.5%)

11 (14.1%)

56 (15.2%)

0.183

Total cholesterol, mmol/L

3.997 ± 0.894

3.859 ± 0.945

3.971 ± 0.946

3.960 ± 1.056

0.890

HDL-C, mmol/L

1.157 ± 0.250

1.120 ± 0.285

1.045 ± 0.206

1.037 ± 0.261

0.004

LDL-C, mmol/L

2.281 ± 0.682

2.139 ± 0.724

2.401 ± 0.788

2.328 ± 0.800

0.286

HbA1c%

6.027 ± 1.071

6.320 ± 0.914

6.394 ± 1.099

6.598 ± 1.176

0.002

Cer (d18:1/16:0), μmol/L

0.226 ± 0.086

0.202 ± 0.075

0.217 ± 0.673

0.223 ± 0.085

0.371

Cer (d18:1/18:0), μmol/L

0.070 ± 0.043

0.057 ± 0.022

0.068 ± 0.030

0.068 ± 0.035

0.280

Cer (d18:1/24:1), μmol/L

2.463 ± 1.007

2.587 ± 0.996

2.620 ± 0.996

2.551 ± 0.993

0.756

Cer (d18:1/24:0), μmol/L

0.746 ± 0.395

0.694 ± 0.241

0.776 ± 0.294

0.782 ± 0.336

0.294

Cer (d18:1/16:0)/Cer (18:1/24:0)

0.096 ± 0.031

0.083 ± 0.026

0.088 ± 0.025

0.092 ± 0.030

0.049

Cer (d18:1/18:0)/Cer (18:1/24:0)

0.029 ± 0.015

0.024 ± 0.011

0.028 ± 0.013

0.028 ± 0.012

0.114

Cer (d18:1/24:1)/Cer (18:1/24:0)

0.322 ± 0.161

0.290 ± 0.130

0.318 ± 0.135

0.329 ± 0.148

0.108

hsCRP, mg/L

0.9(1.37)

0.95(1.507)

1.0(2.085)

1.05(2.32)

0.095

eGFR, mL/min/1.73m2

99.438 ± 14.123

97.974 ± 10.433

94.436 ± 17.180

92.792 ± 18.086

0.003

GRACE score

108.330 ± 23.281

105.945 ± 17.739

105.932 ± 22.645

105.736 ± 26.822

0.381

current medications (statins)

54(90.0%)

46(97.9%)

75(96.2%)

361(98.1%)

0.009

  1. The clinical characteristics in coronary artery stenosis patients. (data is presented as mean ± SD, median and IQR or percentage)