Table 1 Clinical characteristics of the patients
Feature | Adults with FH | Healthy adults | P | Children with FH | Healthy children | P |
|---|---|---|---|---|---|---|
Age [years (SD)] | 37.5 (7.4) | 38.6 (6.4) | 0.5772 | 11.1 (4.5) | 9.8 (4.0) | 0.3148 |
Sex | ||||||
Females [n (%)] | 10 | 10 | 1.000 | 16 | 15 | 0.7924 |
Males [n (%)] | 10 | 10 | 13 | 14 | ||
BMI [kg/m2 (SD)] | 24.2 (1.9) | 23.9 (1.8) | 0.5778 | 18.5 (3.2) | 17.2 (2.1) | 0.1087 |
Smoking (pack years) [years] | 6.26 (2.8) | 6.28 (4.0) | 0.9929 | 0 | 0 | 1.000 |
Hypertension [n (%)] | 7 (35) | 6 (30) | 0.7924 | 0 | 0 | 1.000 |
HbA1C | 4.89 (0.38) | 5.01 (0.15) | 0.1523 | 3.99 (1.29) | 4.23 (1.18) | 0.8473 |
TC | 316.55 (65.57) | 158.52 (16.81) | < 0.0001* | 365.38 (99.23) | 107.30 (18.09) | < 0.0001* |
LDL | 217.50 (53.47) | 80.70 (16.97) | < 0.0001* | 242.45 (58.33) | 57.00 (12.15) | < 0.0001* |
HDL | 68.91 (32.32) | 58.17 (18.67) | 0.1772 | 48.73 (14.82) | 52.30 (8.35) | 0.3128 |
Non-HDL | 247.63 (79.82) | 100.35 (21.07) | < 0.0001 | 316.65 (98.05) | 55.00 (18.70) | < 0.0001 |
TG | 111.63 (25.21) | 93.04 (16.88) | 0.0056* | 99.35 (32.22) | 59.78 (14.33) | < 0.0001* |