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Table 4 Correlations between atherosclerosis surrogates (cumulated data for all subgroups and between parents and children with FH.)

From: “Apple does not fall far from the tree” – subclinical atherosclerosis in children with familial hypercholesterolemia

Parameters

Strain

Strain Rate

R

P

R

P

IMCT

−0.7043

0.0001

−0.6659

0.0001

PWV

−0.8080

0.0001

−0.7788

0.0001

AI

0.8793

0.0001

0.8229

0.0001

Parameters

Children with FH

PWV

AI

Strain

Strain Rate

R

P

R

P

R

P

R

P

Adults with FH

 IMCT

0.5427

0.0091

−0.6520

0.0010

−0.6055

0.0028

−0.6702

0.0006

 PWV

0.6497

0.0011

−0.7891

< 0.0001

−0.6970

0.0003

−0.7113

0.0002

 AI

−0.5629

0.0064

0.6650

0.0007

0.5739

0.0052

0.6231

0.0020

 Strain

−0.5964

0.0034

0.7482

0.0001

0.6374

0.0014

0.7182

0.0002

 Strain Rate

−0.6551

0.0009

0.8113

< 0.0001

0.7248

0.0001

0.7767

< 0.0001

  1. IMCT intima media complex thickness, PVW pulse wave velocity, AI augmentation index, P p-value