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Table 4 Correlations between atherosclerosis surrogates (cumulated data for all subgroups and between parents and children with FH.)

From: “Apple does not fall far from the tree” – subclinical atherosclerosis in children with familial hypercholesterolemia

Parameters Strain Strain Rate
R P R P
IMCT −0.7043 0.0001 −0.6659 0.0001
PWV −0.8080 0.0001 −0.7788 0.0001
AI 0.8793 0.0001 0.8229 0.0001
Parameters Children with FH
PWV AI Strain Strain Rate
R P R P R P R P
Adults with FH
 IMCT 0.5427 0.0091 −0.6520 0.0010 −0.6055 0.0028 −0.6702 0.0006
 PWV 0.6497 0.0011 −0.7891 < 0.0001 −0.6970 0.0003 −0.7113 0.0002
 AI −0.5629 0.0064 0.6650 0.0007 0.5739 0.0052 0.6231 0.0020
 Strain −0.5964 0.0034 0.7482 0.0001 0.6374 0.0014 0.7182 0.0002
 Strain Rate −0.6551 0.0009 0.8113 < 0.0001 0.7248 0.0001 0.7767 < 0.0001
  1. IMCT intima media complex thickness, PVW pulse wave velocity, AI augmentation index, P p-value