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Fig. 4 | Lipids in Health and Disease

Fig. 4

From: Resveratrol intake during pregnancy and lactation re-programs adiposity and ameliorates leptin resistance in male progeny induced by maternal high-fat/high sucrose plus postnatal high-fat/high sucrose diets via fat metabolism regulation

Fig. 4

Gene expression and protein abundance of Sirtuin 1 (SIRT1) in retroperitoneal adipose tissue. a The relative gene expression of SIRT1. b The protein abundance of SIRT1. Illustrative immunoblotting and optical density quantification of SIRT-1 are shown. The relative protein amount was presented as an integrated optical density (IOD)/Ponceau S staining (Pon S). The statistical differences among groups was determined by Two-way ANOVA. Values are mean ± standard error of the mean (SEM) (n = 10–14 for qPCR and n = 8 for western blotting); *compared with CC, p < 0.05; #compared with HC, P < 0.05; §compared with CH, P < 0.05 by a Mann-Whitney U test. The effect of postnatal resveratrol treatment was evaluated by a Mann-Whitney U test; †P < 0.05. (Abbreviations: CC, maternal/postnatal control diet; HC, maternal high-fat/high-sucrose (HFHS)/postnatal control diet; CH, maternal control/postnatal HFHS diet; HH, maternal/postnatal HFHS diet)

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