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Table 4 Multiple Cox analysis on predictive value of estimated RLP-C for composite and each component of adverse event in subgroups with different glycometabolic status

From: Prognostic impact of estimated remnant-like particle cholesterol in patients with differing glycometabolic status: an observational cohort study from China

  As a nominal variablea As a continuous variableb
β HR 95% CI P β HR 95% CI P
Non-diabetic population
 Composite adverse events 0.177 1.193 0.681–2.092 0.538 −0.044 0.957 0.548–1.670 0.876
 All-cause death −1.067 0.344 0.001–229.549 0.748 1.421 4.143 0.240–71.536 0.328
 Non-fatal MI 0.173 1.189 0.382–3.703 0.766 0.088 1.092 0.309–3.855 0.892
 Ischemia-driven revascularization 0.256 1.292 0.664–2.513 0.451 −0.208 0.812 0.421–1.568 0.535
Pre-diabetic population
 Composite adverse events 0.289 1.335 0.852–2.092 0.208 −0.107 0.898 0.577–1.397 0.633
 All-cause death 1.058 2.882 0.337–24.651 0.334 0.124 1.132 0.305–4.202 0.853
 Non-fatal MI 0.297 1.346 0.532–3.404 0.530 0.141 1.152 0.535–2.483 0.718
 Ischemia-driven revascularization 0.271 1.312 0.750–2.293 0.341 −0.321 0.725 0.405–1.297 0.278
Diabetic population
 Composite adverse events 1.446 4.247 2.941–6.135 <  0.001 0.326 1.385 1.183–1.620 <  0.001
 All-cause death 0.452 1.571 0.247–9.996 0.632 −0.284 0.753 0.329–1.723 0.502
 Non-fatal MI 1.804 6.072 2.669–13.815 <  0.001 0.331 1.392 0.975–1.988 0.069
 Ischemia-driven revascularization 1.304 3.683 2.397–5.657 <  0.001 0.283 1.327 1.100–1.600 0.003
  1. Bold values indicate statistically significant associations
  2. Multiple Cox analysis was adjusted for confounders that are significant (P <  0.05) in simple Cox analysis (details shown in Suppl. materials: Table S1)
  3. HR Hazard ratio, CI Confidence interval, MI Myocardial infarction
  4. a The HR was examined regarding the lower median of estimated RLP-C as reference
  5. b The HR was examined by per 1-SD increase of estimated RLP-C