Prognostic impact of estimated remnant-like particle cholesterol in patients with differing glycometabolic status: an observational cohort study from China

Table 4 Multiple Cox analysis on predictive value of estimated RLP-C for composite and each component of adverse event in subgroups with different glycometabolic status

	As a nominal variable^a				As a continuous variable^b
	β	HR	95% CI	P	β	HR	95% CI	P
Non-diabetic population
Composite adverse events	0.177	1.193	0.681–2.092	0.538	−0.044	0.957	0.548–1.670	0.876
All-cause death	−1.067	0.344	0.001–229.549	0.748	1.421	4.143	0.240–71.536	0.328
Non-fatal MI	0.173	1.189	0.382–3.703	0.766	0.088	1.092	0.309–3.855	0.892
Ischemia-driven revascularization	0.256	1.292	0.664–2.513	0.451	−0.208	0.812	0.421–1.568	0.535
Pre-diabetic population
Composite adverse events	0.289	1.335	0.852–2.092	0.208	−0.107	0.898	0.577–1.397	0.633
All-cause death	1.058	2.882	0.337–24.651	0.334	0.124	1.132	0.305–4.202	0.853
Non-fatal MI	0.297	1.346	0.532–3.404	0.530	0.141	1.152	0.535–2.483	0.718
Ischemia-driven revascularization	0.271	1.312	0.750–2.293	0.341	−0.321	0.725	0.405–1.297	0.278
Diabetic population
Composite adverse events	1.446	4.247	2.941–6.135	< 0.001	0.326	1.385	1.183–1.620	< 0.001
All-cause death	0.452	1.571	0.247–9.996	0.632	−0.284	0.753	0.329–1.723	0.502
Non-fatal MI	1.804	6.072	2.669–13.815	< 0.001	0.331	1.392	0.975–1.988	0.069
Ischemia-driven revascularization	1.304	3.683	2.397–5.657	< 0.001	0.283	1.327	1.100–1.600	0.003

Bold values indicate statistically significant associations
Multiple Cox analysis was adjusted for confounders that are significant (P < 0.05) in simple Cox analysis (details shown in Suppl. materials: Table S1)
HR Hazard ratio, CI Confidence interval, MI Myocardial infarction
^a The HR was examined regarding the lower median of estimated RLP-C as reference
^b The HR was examined by per 1-SD increase of estimated RLP-C

ISSN: 1476-511X