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Table 3 Model results for the associations between sleep duration and each abnormal serum lipid level

From: Night sleep duration and risk of each lipid profile abnormality in a Chinese population: a prospective cohort study

Sleep duration (h)

Event, n(%)

Model 1

P value

Model 2

P value

Model 3

P value

Sensitivity analysisa

HR(95% CI)

HR(95% CI)

HR(95% CI)

HR(95% CI)

TC

 ≤ 5

902(43.34)

0.95(0.88–1.02)

0.170

0.95(0.88–1.02)

0.174

0.96(0.89–1.04)

0.331

0.99(0.90–1.10)

 6.0

2397(44.50)

1.00(0.94–1.06)

0.945

1.00(0.94–1.05)

0.893

1.00(0.95–1.06)

0.901

1.06(0.98–1.14)

 7.0

2520(44.81)

reference

 

reference

 

reference

 

reference

 8.0

8741(42.49)

0.93(0.89–0.97)

0.001

0.99(0.94–1.03)

0.527

0.99(0.94–1.04)

0.647

1.06(0.99–1.13)

 ≥ 9

237(39.83)

0.92(0.80–1.05)

0.216

0.92(0.81–1.05)

0.230

0.93(0.81–1.06)

0.278

0.98(0.83–1.16)

TG

 ≤ 5

555(26.67)

0.97(0.88–1.06)

0.495

0.96(0.87–1.05)

0.373

0.99(0.90–1.09)

0.795

1.03(0.91–1.17)

 6.0

1616(30.00)

1.04(0.97–1.11)

0.281

1.03(0.96–1.10)

0.413

1.03(0.97–1.11)

0.338

1.09(0.99–1.19)

 7.0

1702(30.26)

reference

 

reference

 

reference

 

reference

 8.0

6147(29.88)

1.01(0.96–1.06)

0.730

1.05(0.99–1.11)

0.094

1.04(0.98–1.10)

0.174

1.09(1.02–1.18)

 ≥ 9

188(31.60)

1.06(0.91–1.23)

0.445

1.07(0.92–1.24)

0.397

1.07(0.92–1.24)

0.406

1.08(0.89–1.31)

LDL-C

 ≤ 5

405(19.46)

1.03(0.92–1.15)

0.643

1.02 (0.91–1.14)

0.768

1.04(0.93–1.17)

0.515

1.07(0.93–1.23)

 6.0

1031(19.14)

1.03(0.94–1.12)

0.540

1.02(0.94–1.12)

0.584

1.03(0.94–1.12)

0.532

1.08(0.98–1.21)

 7.0

1035(18.40)

reference

 

reference

 

reference

 

reference

 8.0

4269(20.75)

1.18(1.10–1.26)

< 0.001

1.20(1.12–30)

< 0.001

1.21(1.12–1.30)

< 0.001

1.25(1.14–1.36)

 ≥ 9

100(16.81)

1.00(0.81–1.22)

0.969

0.99(0.81–1.22)

0.952

1.00(0.81–1.23)

0.985

0.88(0.67–1.14)

HDL-C

 ≤ 5

1482(71.22)

1.01(0.95–1.07)

0.779

1.01(0.95–1.08)

0.655

1.02(0.96–1.08)

0.605

1.02(0.95–1.09)

 6.0

3658(67.90)

1.01(0.97–1.06)

0.570

1.02(0.97–1.06)

0.505

1.01(0.97–1.06)

0.579

1.02(0.96–1.07)

 7.0

3638(64.69)

reference

 

reference

 

reference

 

reference

 8.0

13,610(66.15)

1.11(1.07–1.16)

< 0.001

1.11(1.07–1.15)

< 0.001

1.10(1.06–1.15)

< 0.001

1.11(1.06–1.16)

 ≥ 9

412(69.24)

1.27(1.15–1.41)

< 0.001

1.27(1.14–1.40)

< 0.001

1.24(1.12–1.38)

< 0.001

1.21(1.07–1.35)

Dyslipidemia

 ≤ 5

1298(62.37)

0.96(0.90–1.02)

0.166

0.96(0.90–1.02)

0.955

0.98(0.92–1.04)

0.471

0.99(0.92–1.08)

 6.0

3558(66.05)

1.04(0.99–1.10)

0.061

1.04(0.99–1.10)

0.061

1.05(1.00–1.10)

0.036

1.07(1.01–1.14)

 7.0

3695(65.70)

reference

 

reference

 

reference

 

reference

 8.0

13,081(63.58)

0.95(0.92–0.99)

0.012

1.01(0.97–1.05)

0.564

1.01(0.97–1.05)

0.509

1.08(1.02–1.14)

 ≥ 9

379(63.70)

0.98(0.88–1.09)

0.681

0.98(0.88–1.09)

0.706

0.98(0.88–1.09)

0.685

1.08(0.95–1.24)

  1. Model 1 adjusted for age and sex
  2. Model 2 was further adjusted for level of education, smoking, alcohol, physical activity, and snoring. Model 3 was further adjusted for hypertension, diabetes mellitus, body mass index, and high-sensitivity C-reactive protein
  3. a Adjusted for model 3 and further excluded individuals with transient changes in lipid profile (e.g., reversion from dyslipidemia to normal blood lipid)
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Lipids in Health and Disease

ISSN: 1476-511X