Association of CYP19A1 and CYP1A2 genetic polymorphisms with type 2 diabetes mellitus risk in the Chinese Han population

Table 1 Demographics and clinical characteristics of cases and controls

Variables	Case (n = 512)	Control (n = 515)	P
Age	59.2 ± 9.6	59.3 ± 11.0	0.990^a
≤ 59	248	243
> 59	264	272
Gender			0.962^b
Male	281	283
Female	231	232
BMI
≤ 24	130	126
> 24	190	123
Tobacco smoking status
Yes	135	132
No	231	137
Alcohol consumption status
Yes	69	98
No	278	138
Disease course
≤ 9	151
> 9	186
Complication
one	108
multiple	141
Antidiabetes drug
Yes	128
No	204
Insulin
Yes	175
No	157
Diabetic retinopathy
Yes	213
No	149
FPG (mmol/L)	9.95 ± 4.69	5.67 ± 0.78	< 0.001^a*
HbA1c (%)	9.30 ± 2.47	5.88 ± 0.79	0.004^a*

The clinical information of participants was partially missing except age, gender and FPG/ HbA1c indexes
BMI body mass index, FPG fasting plasma glucose, HbA1c Hemoglobin A1c
^aP was calculated by t test
^bP was calculated by Pearson’s chi-squared test
*P < 0.05 indicates a significant difference

ISSN: 1476-511X