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Fig. 3 | Lipids in Health and Disease

Fig. 3

From: Brain region–specific lipid alterations in the PLB4 hBACE1 knock-in mouse model of Alzheimer’s disease

Fig. 3

Phospholipid analysis of the PG, PE, and SM content of the PLBWT and PLB4 brain. Analysis of the phosphatidylglycerols (PG), phosphatidylethanolamines (PE), and sphingomyelins (SM) in the PLBWT and PLB4 cortex, hippocampus, and hypothalamus. Each phospholipid class was normalised to its corresponding internal standard. The relative intensity (cps) refers to the normalised total ion count (TIC) for the individual molecular species. Data represented as an average of n = 6. An unpaired, two-tailed Student’s t-test with Welch’s correction was performed to determine statistically significant differences between PLBWT and PLB4 data; * P ≤ 0.05, ** P ≤ 0.01, *** P ≤ 0.001

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