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Fig. 1 | Lipids in Health and Disease

Fig. 1

From: Atherogenic L5 LDL induces cardiomyocyte apoptosis and inhibits KATP channels through CaMKII activation

Fig. 1

Increased apoptosis and decreased cell viability in NRCMs treated with L5. a, Early apoptosis of NRCMs treated with L5, shown by representative images of Hoechst (blue, nuclei), Annexin V-Alexa 488 (green), and PI (red) staining. b, Dose-dependent curve showing the effects of increasing concentrations of L5 and L1 on the percentage of cells staining positive for Annexin V (n = 6 per group). c, Relative apoptosis levels of NRCMs after the indicated treatment, determined by using a caspase-3/7 activity assay (n = 7 per group). d, Cardiomyocyte viability was analyzed after the indicated treatment by using an MTT kit, n = 6 per group. *P < 0.05, **P < 0.01 vs. the PBS-treated group

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Lipids in Health and Disease

ISSN: 1476-511X