The influence of CYP1A1 and CYP1A2 polymorphisms on stroke risk in the Chinese population

Table 5 Haplotype frequencies of CYP1A2 SNPs and the association with stroke risk

	SNP	Haplotype	Frequency		Without adjustment		With adjustment
	SNP	Haplotype	Case	Control	OR(95% CI)	P-values	OR(95% CI)	P-values
Total	rs762551\|rs2470890	AT	0.876	0.882	0.95 (0.72–1.25)	0.688	0.95 (0.72–1.25)	0.718
	rs762551\|rs2470890	CC	0.380	0.427	0.82 (0.68–0.99)	0.035^*	0.82 (0.68–0.99)	0.034^*
	rs762551\|rs2470890	AC	0.504	0.545	0.85 (0.71–1.02)	0.076	0.85 (0.71–1.01)	0.070
Hypertension	rs762551\|rs2470890	AT	0.861	0.912	0.60 (0.37–0.96)	0.032^*	0.60 (0.37–0.96)	0.033^*
	rs762551\|rs2470890	CC	0.395	0.343	1.28 (0.94–1.74)	0.117	1.29 (0.94–1.75)	0.113
	rs762551\|rs2470890	AC	0.534	0.431	1.56 (1.16–2.10)	0.003^*	1.57 (1.16–2.11)	0.003^*

OR Odds ratio, 95% CIs 95% confidence intervals
P-values were calculated by logistic regression with adjustment for age and gender
^*Bold-face values indicated statistical significance (P < 0.05)

ISSN: 1476-511X