Genotypes | *15/*15 | *1a/*15 | *1a/*1a | *1a/*1b | *1a/*5 | *1b/*15 | *1b/*1b |
All subjects | 23 (1.17%) | 117 (5.95%) | 107 (5.44%) | 639 (32.50%) | 1 (0.05%) | 265 (13.48%) | 814 (41.40%) |
 Patients(n = 938) | 11 (1.17%) | 63 (6.72%) | 55 (5.86%) | 316 (33.69%) | 1 (0.11%) | 129 (13.75%) | 363 (38.70%) |
 Controls(n = 1028) | 12 (1.17%) | 54 (5.25%) | 52 (5.06%) | 323 (31.42%) | 0 (0) | 136 (13.23%) | 451 (43.87%) |
 P values (Patients vs controls) | 0.991 | 0.171 | 0.432 | 0.283 | 0.477 | 0.734 | 0.020 |
Males | |||||||
 Patients(n = 581) | 8 (1.38%) | 40 (6.88%) | 35 (6.02%) | 199 (34.25%) | 1 (0.17%) | 79 (13.60%) | 219 (37.69%) |
 Controls(n = 622) | 11 (1.77%) | 36 (5.79%) | 35 (5.63%) | 190 (30.55%) | 0 (0) | 85 (13.67%) | 265 (42.60%) |
 P values (Patients vs controls) | 0.586 | 0.435 | 0.769 | 0.170 | 0.483 | 0.972 | 0.083 |
Females | |||||||
 Patients(n = 357) | 3 (0.84%) | 23 (6.44%) | 20 (5.60%) | 117 (32.77%) | 0 (0) | 50 (14.01%) | 144 (40.34%) |
 Controls(n = 406) | 1 (0.25%) | 18 (4.43%) | 17 (4.19%) | 133 (32.76%) | 0 (0) | 51 (12.56%) | 186 (45.81%) |
 P values (Patients vs controls) | – | 0.219 | 0.364 | 0.997 | – | 0.557 | 0.128 |
Alleles | *15 | *5 | *1a | *1b | Â | Â | Â |
All subjects(n = 3932) | 428 (10.89%) | 1 (0.03%) | 971 (24.69%) | 2532 (64.39%) |  |  |  |
 Patients(n = 1876) | 214 (11.41%) | 1 (0.05%) | 490 (26.12%) | 1171 (62.42%) |  |  |  |
 Controls(n = 2056) | 214 (10.41%) | 0 (0) | 481 (23.39%) | 1361 (66.20%) |  |  |  |
 P values (Patients vs controls) | 0.315 | 0.477 | 0.048 | 0.014 |  |  |  |
Males | |||||||
 Patients(n = 1162) | 135 (11.62%) | 1 (0.09%) | 310 (26.68%) | 716 (61.62%) |  |  |  |
 Controls(n = 1244) | 143 (11.50%) | 0 (0) | 296 (23.79%) | 805 (64.71%) |  |  |  |
 P values (Patients vs controls) | 0.925 | 0.483 | 0.103 | 0.116 |  |  |  |
Females | |||||||
 Patients(n = 714) | 79 (11.06%) | 0 (0) | 180 (25.21%) | 455 (63.73%) |  |  |  |
 Controls(n = 812) | 71 (8.74%) | 0 (0) | 185 (22.78%) | 556 (68.47%) |  |  |  |
 P values (Patients vs controls) | 0.129 | – | 0.267 | 0.051 |  |  |  |