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Table 3 Genotypes and allele distribution of SLCO1B1 gene in cerebral infarction patients and control participants in total and according to gender

From: The SNPs rs429358 and rs7412 of APOE gene are association with cerebral infarction but not SNPs rs2306283 and rs4149056 of SLCO1B1 gene in southern Chinese Hakka population

Genotypes

*15/*15

*1a/*15

*1a/*1a

*1a/*1b

*1a/*5

*1b/*15

*1b/*1b

All subjects

23 (1.17%)

117 (5.95%)

107 (5.44%)

639 (32.50%)

1 (0.05%)

265 (13.48%)

814 (41.40%)

 Patients(n = 938)

11 (1.17%)

63 (6.72%)

55 (5.86%)

316 (33.69%)

1 (0.11%)

129 (13.75%)

363 (38.70%)

 Controls(n = 1028)

12 (1.17%)

54 (5.25%)

52 (5.06%)

323 (31.42%)

0 (0)

136 (13.23%)

451 (43.87%)

 P values (Patients vs controls)

0.991

0.171

0.432

0.283

0.477

0.734

0.020

Males

 Patients(n = 581)

8 (1.38%)

40 (6.88%)

35 (6.02%)

199 (34.25%)

1 (0.17%)

79 (13.60%)

219 (37.69%)

 Controls(n = 622)

11 (1.77%)

36 (5.79%)

35 (5.63%)

190 (30.55%)

0 (0)

85 (13.67%)

265 (42.60%)

 P values (Patients vs controls)

0.586

0.435

0.769

0.170

0.483

0.972

0.083

Females

 Patients(n = 357)

3 (0.84%)

23 (6.44%)

20 (5.60%)

117 (32.77%)

0 (0)

50 (14.01%)

144 (40.34%)

 Controls(n = 406)

1 (0.25%)

18 (4.43%)

17 (4.19%)

133 (32.76%)

0 (0)

51 (12.56%)

186 (45.81%)

 P values (Patients vs controls)

–

0.219

0.364

0.997

–

0.557

0.128

Alleles

*15

*5

*1a

*1b

   

All subjects(n = 3932)

428 (10.89%)

1 (0.03%)

971 (24.69%)

2532 (64.39%)

   

 Patients(n = 1876)

214 (11.41%)

1 (0.05%)

490 (26.12%)

1171 (62.42%)

   

 Controls(n = 2056)

214 (10.41%)

0 (0)

481 (23.39%)

1361 (66.20%)

   

 P values (Patients vs controls)

0.315

0.477

0.048

0.014

   

Males

 Patients(n = 1162)

135 (11.62%)

1 (0.09%)

310 (26.68%)

716 (61.62%)

   

 Controls(n = 1244)

143 (11.50%)

0 (0)

296 (23.79%)

805 (64.71%)

   

 P values (Patients vs controls)

0.925

0.483

0.103

0.116

   

Females

 Patients(n = 714)

79 (11.06%)

0 (0)

180 (25.21%)

455 (63.73%)

   

 Controls(n = 812)

71 (8.74%)

0 (0)

185 (22.78%)

556 (68.47%)

   

 P values (Patients vs controls)

0.129

–

0.267

0.051

   
  1. Numbers in parentheses are percentages