Skip to main content

Table 1 Baseline characteristics of non-valvular atrial fibrillation patients with and without ischaemic stroke

From: LDL-C/HDL-C is associated with ischaemic stroke in patients with non-valvular atrial fibrillation: a case-control study

Demographic characteristics Stroke t/χ2/Z P
Yes (n = 798) No (n = 2671)
Gender
 Women, n (%) 305 (38.22) 825 (30.89) 15.04 < 0.01
 Men, n (%) 493 (61.78) 1846 (69.11)
Age, year 71.64 ± 9.96 67.30 ± 12.01 −10.28 < 0.01
Body mass index, kg/m2 25.20 ± 3.26 24.75 ± 3.35 −3.35 < 0.01
Hypertension, n (%) 352 (44.11) 907 (33.96) 27.39 < 0.01
Diabetes mellitus,n (%) 171 (21.43) 531 (19.88) 0.91 0.34
Heart failure, n (%) 424 (53.13) 1510 (56.53) 2.88 0.09
Vascular disease, n (%) 121 (15.16) 263 (9.85) 17.64 < 0.01
CHA2DS2-VASc score, mean 4.96 ± 1.37 2.47 ± 1.40 −44.45 < 0.01
Smoking, n (%) 269 (33.71) 660 (24.71) 25.38 < 0.01
Drinking, n (%) 124 (15.54) 371 (13.89) 1.37 0.24
TG, mmol/L 1.11 ± 0.67 1.14 ± 0.89 1.08 0.28
TC, mmol/L 3.57 ± 1.29 3.48 ± 1.47 −1.55 0.12
non-HDL-C, mmol/L 2.65 ± 1.25 2.48 ± 1.42 −3.10 < 0.01
LDL-C, mmol/L 2.58 ± 1.02 1.69 ± 0.86 −22.18 < 0.01
HDL-C, mmol/L 0.92 ± 0.39 1.00 ± 0.34 5.47 < 0.01
LDL-C/HDL-C 2.83 (1.83, 4.09) 1.55 (1.10, 2.27) −22.17 < 0.01
Uric acid, umol/L 278.54 ± 147.06 295.71 ± 145.64 2.92 < 0.01
Creatinine, mmol/L 75.44 ± 37.23 76.00 ± 59.92 0.32 0.75
Blood urea nitrogen, mmol/L 5.97 ± 2.68 6.05 ± 2.77 0.67 0.50
Fasting plasma glucose, mmol/L 5.93 ± 2.44 5.75 ± 2.29 −1.92 0.06
Previous Medications
 Anti-hypertensive drugs, n (%) 287 (35.96) 754 (28.23) 17.51 < 0.01
 Anti-diabetic agents, n (%) 141 (17.67) 420 (15.72) 1.71 0.19
 Statins, n (%) 85 (10.65) 345 (12.92) 2.90 0.09
 anti-platelet drugs, n (%) 150 (18.80) 583 (21.83) 3.39 0.07
 anticoagulant drugs, n (%) 189 (23.68) 656 (24.56) 0.26 0.61
  1. HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, non-HDL-C non-high-density lipoprotein cholesterol, TC total cholesterol, TG triglycerides