Skip to main content

Table 1 Baseline characteristics of non-valvular atrial fibrillation patients with and without ischaemic stroke

From: LDL-C/HDL-C is associated with ischaemic stroke in patients with non-valvular atrial fibrillation: a case-control study

Demographic characteristics

Stroke

t/χ2/Z

P

Yes (n = 798)

No (n = 2671)

Gender

 Women, n (%)

305 (38.22)

825 (30.89)

15.04

< 0.01

 Men, n (%)

493 (61.78)

1846 (69.11)

Age, year

71.64 ± 9.96

67.30 ± 12.01

−10.28

< 0.01

Body mass index, kg/m2

25.20 ± 3.26

24.75 ± 3.35

−3.35

< 0.01

Hypertension, n (%)

352 (44.11)

907 (33.96)

27.39

< 0.01

Diabetes mellitus,n (%)

171 (21.43)

531 (19.88)

0.91

0.34

Heart failure, n (%)

424 (53.13)

1510 (56.53)

2.88

0.09

Vascular disease, n (%)

121 (15.16)

263 (9.85)

17.64

< 0.01

CHA2DS2-VASc score, mean

4.96 ± 1.37

2.47 ± 1.40

−44.45

< 0.01

Smoking, n (%)

269 (33.71)

660 (24.71)

25.38

< 0.01

Drinking, n (%)

124 (15.54)

371 (13.89)

1.37

0.24

TG, mmol/L

1.11 ± 0.67

1.14 ± 0.89

1.08

0.28

TC, mmol/L

3.57 ± 1.29

3.48 ± 1.47

−1.55

0.12

non-HDL-C, mmol/L

2.65 ± 1.25

2.48 ± 1.42

−3.10

< 0.01

LDL-C, mmol/L

2.58 ± 1.02

1.69 ± 0.86

−22.18

< 0.01

HDL-C, mmol/L

0.92 ± 0.39

1.00 ± 0.34

5.47

< 0.01

LDL-C/HDL-C

2.83 (1.83, 4.09)

1.55 (1.10, 2.27)

−22.17

< 0.01

Uric acid, umol/L

278.54 ± 147.06

295.71 ± 145.64

2.92

< 0.01

Creatinine, mmol/L

75.44 ± 37.23

76.00 ± 59.92

0.32

0.75

Blood urea nitrogen, mmol/L

5.97 ± 2.68

6.05 ± 2.77

0.67

0.50

Fasting plasma glucose, mmol/L

5.93 ± 2.44

5.75 ± 2.29

−1.92

0.06

Previous Medications

 Anti-hypertensive drugs, n (%)

287 (35.96)

754 (28.23)

17.51

< 0.01

 Anti-diabetic agents, n (%)

141 (17.67)

420 (15.72)

1.71

0.19

 Statins, n (%)

85 (10.65)

345 (12.92)

2.90

0.09

 anti-platelet drugs, n (%)

150 (18.80)

583 (21.83)

3.39

0.07

 anticoagulant drugs, n (%)

189 (23.68)

656 (24.56)

0.26

0.61

  1. HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, non-HDL-C non-high-density lipoprotein cholesterol, TC total cholesterol, TG triglycerides