Skip to main content

Table 2 Univariate logistic regression analysis for risk factors of ischaemic stroke

From: LDL-C/HDL-C is associated with ischaemic stroke in patients with non-valvular atrial fibrillation: a case-control study

Characteristic β SE Waldχ2 OR 95% CI P
Age (years)
  < 65 Reference      
 65 to 74 0.57 0.11 27.74 1.77 1.43, 2.20 < 0.01
  ≥ 75 0.89 0.11 72.50 2.44 1.99, 3.00 < 0.01
Women 0.33 0.08 14.98 1.38 1.17, 1.63 < 0.01
Hypertension 0.43 0.08 27.19 1.54 1.31, 1.80 < 0.01
Diabetes mellitus 0.10 0.10 0.91 1.10 0.91, 1.33 0.34
Vascular disease 0.49 0.12 17.38 1.64 1.30, 2.06 < 0.01
CHA2DS2-VASc score 1.27 0.05 724.32 3.55 3.24, 3.90 < 0.01
Smoking 0.44 0.09 25.16 1.55 1.31, 1.84 < 0.01
Drinking 0.13 0.11 1.36 1.14 0.92, 1.42 0.24
Heart failure −0.14 0.08 2.88 0.87 0.74, 1.02 0.09
TG (mmol/L)
  ≤ 2.26 Reference      
  > 2.26 −0.19 0.21 0.77 0.83 0.55, 1.26 0.38
TC (mmol/L)
  ≤ 6.22 Reference      
  > 6.22 0.16 0.31 0.26 1.18 0.64, 2.17 0.61
non-HDL-C (mmol/L) 0.09 0.03 9.03 1.09 1.03, 1.16 < 0.01
LDL-C (mmol/L)
  ≤ 4.14 Reference      
  > 4.14 1.72 0.23 54.25 5.57 3.53, 8.80 < 0.01
HDL-C (mmol/L)
  ≥ 1.04 −2.05 0.08 6.47 0.81 0.70, 0.95 0.01
  < 1.04 Reference      
LDL-C/HDL-C
 First quartile (< 1.22) Reference      
 Second quartile [1.22, 1.71) 0.69 0.17 16.48 2.00 1.43, 2.79 < 0.01
 Third quartile [1.71, 2.73) 1.48 0.16 88.09 4.39 3.22, 5.79 < 0.01
 Fourth quartile (≥2.73) 2.58 0.15 289.19 13.26 9.84, 17.86 < 0.01
Body mass index (kg/m2)
  < 24 Reference      
  [24, 28) 0.43 0.09 23.18 1.54 1.29, 1.83 < 0.01
  ≥ 28 0.34 0.12 7.77 1.41 1.11, 1.79 < 0.01
Uric acid (umol/L) −0.001 0.00 8.46 1.00 0.999, 1.000 < 0.01
Creatinine (mmol/L) 0.00 0.001 0.06 1.00 0.998, 1.001 0.80
Blood urea nitrogen (mmol/L) −0.01 0.02 0.45 0.99 0.96, 1.02 0.50
Fasting plasma glucose (mmol/L)
  < 7 Reference      
  ≥ 7 0.13 0.10 1.62 1.13 0.94, 1.38 0.20
  1. HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, non-HDL-C non-high-density lipoprotein cholesterol, TC total cholesterol, TG triglycerides, 95% CI 95% confidence interval, OR odds ratio, SE standard error