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Table 4 Multivariable adjusted odds ratios of LDL-C/HDL-C quartiles in relation to risk factor of ischaemic stroke

From: LDL-C/HDL-C is associated with ischaemic stroke in patients with non-valvular atrial fibrillation: a case-control study

Variables LDL-C/HDL-C quartiles P
Q1 (n = 865) Q2 (n = 869) Q3 (n = 868) Q4 (n = 867)
ischaemic stroke case, n (%) 58 (7.27) 109 (13.66) 208 (26.07) 423 (53.00) < 0.01
Range of LDL-C/HDL-C quartile < 1.22 [1.22, 1.71) [1.71, 2.73) ≥2.73  
Model1 1.00 2.14 (1.53, 2.99) 5.11 (3.73, 6.99) 16.00 (11.79, 21.71) < 0.01
Model2 1.00 2.37 (1.60, 3.53) 6.05 (4.13, 8.84) 17.34 (11.87, 25.32) < 0.01
Model3 1.00 2.56 (1.82, 3.62) 6.19 (4.46, 8.60) 24.45 (17.18, 34.79) < 0.01
  1. Model1 adjusted for age and sex; Model2 adjusted for CHA2DS2-VASc score; Model3 adjusted for blood urea nitrogen, BMI, creatinine, drinking, fasting plasma glucose, non-HDL-C, smoking, triglyceride, total cholesterol, and uric acid. Abbreviations: BMI body mass index, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, non-HDL-C non-high-density lipoprotein cholesterol