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Fig. 1 | Lipids in Health and Disease

Fig. 1

From: Hyperhomocysteinemia and dyslipidemia in point mutation G307S of cystathionine β-synthase-deficient rabbit generated using CRISPR/Cas9

Fig. 1

Homology-dependent repair (HDR) knock-in of CBS gene in rabbits using CRISPR/Cas9 gene editing. a CRISPR/Cas9-targeting sites on the rabbit CBS gene. The red letters in the sgRNA sequences are specific for exon 8, and the green letters indicate the protospacer adjacent motif (PAM). b Donor template sequences with silent mutations (green letters) and G307S (red letters)

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Lipids in Health and Disease

ISSN: 1476-511X