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Table 1 Baseline characteristics compared between users and non-users of LLD and AHD

From: Higher levels of the soluble receptor for advanced glycation end products and lower levels of the extracellular newly identified receptor for advanced glycation end products were associated with lipid-lowering drugs in patients with type 1 diabetes: a comparative cross-sectional study

 

All patients a

Users of lipid-lowering drugs b

Users of antihypertensive drugs

Yes

No

P value c

Yes

No

P value c

N

283

130

153

–

89

194

–

Age, years

(18–59)

48 (42, 54)

34 (27, 44)

<  0.001

49 (42, 56)

38 (29, 47)

<  0.001

Diabetes duration, years

(1–55)

26 (14, 35)

17 (9, 23)

<  0.001

29 (20, 36)

16 (9, 25)

<  0.001

Sex

 Women

124 (44)

54 (42)

70 (46)

0.55

31 (35)

93 (48)

0.040

 Men

159 (56)

76 (58)

83 (54)

58 (65)

101 (52)

Abdominal obesity e

46 (16)

29 (23)

17 (11)

0.015 d

20 (23)

26 (14)

0.082

General obesity f

34 (12)

16 (12)

18 (12)

>  0.99 d

10 (11)

24 (12)

0.85

Hypoglycemia, severe episodes

12 (4)

7 (5)

5 (3)

0.39 d

2 (2)

10 (5)

0.35

Systolic BP, mmHg

(90–160)

125 (119, 135)

120 (110, 130)

<  0.001

130 (125, 138)

120 (110, 125)

<  0.001

Diastolic BP, mmHg

(55–100)

70 (70, 75)

70 (65, 75)

0.44

70 (70, 79)

70 (65, 75)

0.007

Depression

29 (10)

14 (11)

15 (10)

0.84

10 (11)

19 (10)

0.68

Smoking g

28 (10)

13 (10)

15 (11)

>  0.99 d

6 (7)

22 (12)

0.28

Physical inactivity h

29 (11)

10 (8)

19 (14)

0.17 d

8 (9)

21 (12)

0.68

Continuous subcutaneous insulin infusion

25 (9)

10 (8)

15 (10)

0.68d

7 (8)

18 (9)

0.82

Lipid-lowering drugs

130 (46)

–

–

 

58 (65)

72 (37)

<  0.001

Antihypertensive drugs

89 (31)

58 (45)

31 (20)

<  0.001 d

–

–

–

Antidepressants

22 (8)

15 (12)

7 (5)

0.043

9 (10)

13 (7)

0.34

Corticosteroids, nasal or inhaled

26 (9)

13 (10)

13 (8)

0.68

10 (11)

16 (8)

0.51

Cardiovascular complications

10 (4)

9 (7)

1 (1)

0.007 d

7 (8)

3 (2)

0.013

  1. a Data are presented as (min-max) or N (%). b Data are presented as N (%) or median (q1, q3)
  2. c Mann-Whitney U test unless otherwise indicated. d Fisher’s exact test. Missing values (N): e 6; f 2; g, h 16