| All patients a | Users of lipid-lowering drugs b | Users of antihypertensive drugs | ||||
---|---|---|---|---|---|---|---|
Yes | No | P value c | Yes | No | P value c | ||
N | 283 | 130 | 153 | – | 89 | 194 | – |
EN-RAGE d, μg/L | (1.5–907) | 11.8 (6.8, 18.8) | 13.7 (8.0, 24.9) | 0.060 | 12.8 (7.0, 18.9) | 13.2 (7.4, 23.4) | 0.48 |
sRAGE e, μg/L | (0.2–105) | 1.3 (0.8, 2.0) | 1.3 (0.8, 1.8) | 0.38 | 1.1 (0.6, 1.7) | 1.3 (0.9, 1.9) | 0.031 |
EN-RAGE/sRAGE ratio f | (0.4–756) | 7.9 (4.0, 17.7) | 11.7 (6.7, 22.8) | 0.009 | 10.8 (4.5, 29.4) | 10.0 (5.3, 17.4) | 0.19 |
CRP g, mg/L | (0.03–8.9) | 0.5 (0.2, 1.7) | 0.8 (0.3, 1.6) | 0.67 | 0.6 (0.3, 1.7) | 0.7 (0.3, 1.7) | 0.86 |
HbA1c | |||||||
 mmol/mol | (25–110) | 64 (56, 72) | 61 (53, 69) | 0.022 | 65 (55, 72) | 60 (54, 71) | 0.090 |
 % | (4.4–12.2) | 8.0 (7.3, 8.7) | 7.8 (7.0, 8.5) | 8.1 (7.2, 8.8) | 7.7 (7.1, 8.6) | ||
Total cholesterol, mmol/L | (2.1–10.9) | 4.5 (4.0, 5.2) | 4.6 (4.1, 5.2) | 0.37 | 4.7 (4.0, 5.3) | 4.6 (4.1, 5.1) | 0.69 |
Triglycerides, mmol/L | (0.1–5.9) | 1.0 (0.7, 1.3) | 0.8 (0.7, 1.1) | 0.016 | 1.0 (0.7, 1.4) | 0.9 (0.6, 1.2) | 0.043 |
LDL-cholesterol, mmol/L | (0.6–8.3) | 2.7 (2.3, 3.3) | 2.9 (2.4, 3.3) | 0.12 | 2.8 (2.3, 3.4) | 2.8 (2.4, 3.3) | 0.98 |
HDL-cholesterol, mmol/L | (0.3–2.7) | 1.5 (1.3, 1.8) | 1.5 (1.3, 1.8) | 0.52 | 1.5 (1.3, 1.8) | 1.5 (1.3, 1.8) | 0.60 |
S-creatinine h, μmol/L | (28–182) | 71 (64, 80) | 69 (61, 76) | 0.088 | 72 (63, 81) | 69 (61, 77) | 0.022 |