Table 1 Baseline parameters of population (N = 201,298)
TyG index | Q1 (<7.93) | Q2 (≥7.93 to <8.31) | Q3 (≥8.31 to <8.73) | Q4 (≥8.73) | P-value |
|---|---|---|---|---|---|
Participants | 49,413 | 50,766 | 49,852 | 51,267 | Â |
Age (years, mean ± SD) | 37.32 ± 9.93 | 40.48 ± 12.00 | 43.76 ± 13.26 | 46.61 ± 13.20 | < 0.001 |
Sex, n (%). |  |  |  |  | < 0.001 |
 Male | 16,016 (32.41) | 24,391 (48.05) | 30,683 (61.55) | 38,146 (74.41) |  |
 Female | 33,397 (67.59) | 26,375 (51.95) | 19,169 (38.45) | 13,121 (25.59) |  |
BMI (kg/m2, mean ± SD) | 21.26 ± 2.59 | 22.40 ± 2.95 | 23.71 ± 3.13 | 25.31 ± 3.11 | < 0.001 |
SBP (mmHg, mean ± SD) | 112.37 ± 14.02 | 116.50 ± 15.29 | 120.82 ± 16.07 | 125.62 ± 16.64 | < 0.001 |
DBP (mmHg, mean ± SD) | 69.98 ± 9.53 | 72.45 ± 10.09 | 75.10 ± 10.51 | 78.47 ± 10.92 | < 0.001 |
FPG (mg/dL, mean ± SD) | 83.49 ± 9.29 | 86.88 ± 9.40 | 89.61 ± 9.75 | 93.58 ± 10.48 | < 0.001 |
TC (mg/dL, mean ± SD) | 165.41 ± 28.64 | 175.71 ± 30.75 | 185.95 ± 32.89 | 198.45 ± 34.94 | < 0.001 |
TG (mg/dL, mean ± SD) | 51.00 ± 11.26 | 78.87 ± 12.03 | 113.51 ± 18.14 | 199.82 ± 58.97 | < 0.001 |
LDL-C (mg/dL, mean ± SD) | 79.28 ± 22.93 | 85.06 ± 27.52 | 90.81 ± 31.54 | 95.18 ± 34.56 | < 0.001 |
HDL-C (mg/dL, mean ± SD) | 53.17 ± 11.91 | 53.09 ± 11.82 | 53.08 ± 11.90 | 53.07 ± 11.79 | 0.769 |
ALT (IU/L, median (Q1-Q3) | 13.90 (10.90–18.60) | 16.00 (12.00–22.80) | 19.05 (14.00–28.00) | 25.40 (18.00–38.30) | < 0.001 |
AST (IU/L, mean ± SD) | 21.74 ± 6.05 | 22.25 ± 6.41 | 22.95 ± 6.75 | 24.25 ± 8.22 | < 0.001 |
Scr (mg/dL, mean ± SD) | 0.73 ± 0.15 | 0.77 ± 0.16 | 0.81 ± 0.16 | 0.84 ± 0.16 | < 0.001 |
Smoker |  |  |  |  | < 0.001 |
 Now | 1011 (2.05) | 2096 (4.13) | 3140 (6.30) | 4824 (9.41) |  |
 Once | 304 (0.62) | 536 (1.06) | 732 (1.47) | 847 (1.65) |  |
 Never | 10,591 (21.43) | 11,372 (22.40) | 10,978 (22.02) | 10,556 (20.59) |  |
 Not recorded | 37,507 (75.90) | 36,762 (72.41) | 35,002 (70.21) | 35,040 (68.35) |  |
Drinker |  |  |  |  | < 0.001 |
 Now | 108 (0.22) | 225 (0.44) | 329 (0.66) | 581 (1.13) |  |
 Once | 1180 (2.39) | 1831 (3.61) | 2357 (4.73) | 3128 (6.10) |  |
 Never | 10,618 (21.48) | 11,948 (23.54) | 12,164 (24.40) | 12,518 (24.42) |  |
 Not recorded | 37,507 (75.91) | 36,762 (72.41) | 35,002 (70.21) | 35,040 (68.35) |  |
Family history of diabetes, n (%) |  |  |  |  | < 0.001 |
 No | 48,526 (98.20) | 49,708 (97.92) | 48,804 (97.90) | 50,158 (97.84) |  |
 Yes | 887 (1.80) | 1058 (2.08) | 1048 (2.10) | 1109 (2.16) |  |