Characterization of the serum levels of Meteorin-like in patients with inflammatory bowel disease and its association with inflammatory cytokines

Table 1 Anthropometric and biochemical characteristic of studied population

	Control (n = 54)	UC (n = 42)	CD (n = 43)	P value
Sex (male/female)	42/12	31/11	28/15	0.373
BMI (kg/m2)	24.12 ± 3.56	23.45 ± 3.64	24.43 ± 4.61	0.502
Normal weight / over weight	29/25	26/16	21/22	0.473
Age (year)	39.02 ± 4.6	38.24 ± 5.32	38.74 ± 5.7	0.763
SBP (mmHg)	131.17 ± 20.79	133.40 ± 24.26	131.65 ± 23.97	0.887
DBP (mmHg)	81.63 ± 13.11	83.10 ± 14.48	83.16 ± 14.26	0.825
FBG (mg/dL)	90.26 ± 9.03	93.65 ± 13.27	94.28 ± 12.05	0.172
Insulin (μU/mL)	4.03 ± 0.31	5.66 ± 0.5	5.93 ± 0.64^b*	0.014
HOMA-IR	0.89 ± 0.07	1.31 ± 0.14	1.43 ± 0.17^b**	0.005
TG (mg/dL)	117.41 ± 44.83	128.76 ± 47.64	126.08 ± 38.15	0.409
TC (mg/dL)	157.22 ± 35.41	164.54 ± 47.49	162.25 ± 30.83	0.629
LDL-C (mg/dL)	94.70 ± 26.95	100.64 ± 35.84	104.93 ± 21.74	0.212
HDL-C (mg/dL)	43.53 ± 6.20	42.11 ± 9.07	41.46 ± 7.76	0.394
Adiponectin (μg/mL)	10.29 ± 3.35	7.88 ± 2.83^a**	7.44 ± 2.44^b**	< 0.001
TNF-α (pg/mL)	16.08 ± 5.50	29.62 ± 7.40^a**	30.43 ± 8.25^b**	< 0.001
IL-6 (pg/mL)	6.38 ± 3.51	8.28 ± 4.11	9.17 ± 4.18^b**	0.002
Metrnl (pg/mL)	107.52 ± 35.33	76.93 ± 27.92^a**	85.25 ± 36.55^b**	< 0.001

Data are presented as Mean ± SD
One way ANOVA and Tukey’s multiple comparisons test were used for comparison of quantitative variables
Abbreviations: UC ulcerative colitis, CD Crohn’s disease, SBP systolic blood pressure, DBP diastolic blood pressure, FBG fasting blood glucose, HOMA-IR homeostasis model assessment of insulin resistance, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, TC total cholesterol, TG triglyceride
^a Comparison between control and UC
^b Comparison between control and CD
*P < 0.05
**P < 0.01

ISSN: 1476-511X