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Table 2 Odds ratio of PAD according to continuous or tertiles of nontraditional lipid profiles

From: Association between nontraditional lipid profiles and peripheral arterial disease in Chinese adults with hypertension

Variables

N

Events, n(%)

Crude

 

Model 1

 

OR (95%CI)

P value

OR (95%CI)

P value

TC/HDL-C ratio (Per 1 SD increase)

10,900

310 (2.8%)

1.20 (1.08, 1.34)

< 0.001

1.37 (1.22, 1.54)

< 0.001

Tertiles of TC/HDL-C ratio

 T1(< 3.0)

3633

90 (2.5%)

1.00 (reference)

 

1.00 (reference)

 

 T2(3.0–3.7)

3633

103 (2.8%)

1.15 (0.86, 1.53)

0.343

1.36 (1.01, 1.84)

0.045

 T3(≥3.7)

3634

117 (3.2%)

1.31 (0.99, 1.73)

0.058

1.77 (1.31, 2.40)

< 0.001

 P for trend

   

0.057

 

< 0.001

TG/HDL-C ratio (Per 1 SD increase)

10,900

310 (2.8%)

0.93 (0.82, 1.06)

0.302

1.14 (1.01, 1.29)

0.029

Tertiles of TG/HDL-C ratio

 T1(< 0.7)

3633

100 (2.8%)

1.00 (reference)

 

1.00 (reference)

 

 T2(0.7–1.3)

3633

106 (2.9%)

1.06 (0.80, 1.40)

0.672

1.27 (0.95, 1.70)

0.111

 T3(≥1.3)

3634

104 (2.9%)

1.04 (0.79, 1.38)

0.778

1.71 (1.25, 2.34)

< 0.001

 P for trend

   

0.779

 

< 0.001

LDL/HDL-C ratio (Per 1 SD increase)

10,900

310 (2.8%)

1.22 (1.10, 1.36)

< 0.001

1.40 (1.25, 1.57)

< 0.001

Tertiles of LDL/HDL-C ratio

 T1(< 1.7)

3633

91 (2.5%)

1.00 (reference)

 

1.00 (reference)

 

 T2(1.7–2.2)

3632

91 (2.5%)

1.00 (0.75, 1.34)

0.999

1.23 (0.91, 1.68)

0.182

 T3(≥2.2)

3635

128 (3.5%)

1.42 (1.08, 1.87)

0.012

2.03 (1.50, 2.74)

< 0.001

 P for trend

   

0.009

 

< 0.001

Non-HDL-C (Per 1 SD increase)

10,900

310 (2.8%)

1.08 (0.97, 1.21)

0.163

1.24 (1.10, 1.39)

< 0.001

Tertiles of Non-HDL-C

 T1(< 3.1)

3621

90 (2.5%)

1.00 (reference)

 

1.00 (reference)

 

 T2(3.1–3.9)

3633

112 (3.1%)

1.25 (0.94, 1.65)

0.123

1.58 (1.17, 2.12)

0.003

 T3(≥3.9)

3646

108 (3.0%)

1.20 (0.90, 1.59)

0.213

1.70 (1.25, 2.31)

< 0.001

 P for trend

   

0.223

 

< 0.001

  1. Model 1 was adjusted for age, sex, BMI, SBP, DBP, smoking status, alcohol drinking status, fasting glucose, total homocysteine, eGFR, self-reported diabetes, self-reported stroke, lipoprotein-lowering drugs, and antihypertensive drugs
  2. Abbreviations: PAD Peripheral arterial disease; OR Odd ratio; 95% CI 95% Confidence interval; TC Total cholesterol; TG Triglyceride; HDL-C High-density lipoprotein cholesterol; LDL-C Low-density lipoprotein cholesterol; non-HDL-C Non-high-density lipoprotein cholesterol